MYL2 抗体
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北京 101111
Quick Overview for MYL2 抗体 (ABIN969302)
抗原
See all MYL2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MYL2 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of MYL2 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 14, Issue 5, pp. 339-50, (2004) (PubMed).
: "Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells." in: Oncogene, Vol. 21, Issue 38, pp. 5852-60, (2002) (PubMed).
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- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
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别名
- MYL2
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背景
- MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
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分子量
- 19 kDa
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基因ID
- 4633
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UniProt
- P10916
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途径
- Myometrial Relaxation and Contraction
抗原
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