(2 references)-
- 抗原 See all FCER2 抗体
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FCER2 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human FCER2 expressed in E. coli.
- 克隆位点
- 5B5
- 亚型
- IgG1
- Top Product
- Discover our top product FCER2 Primary Antibody
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anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 151-321) antibody
FCER2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 150-330) antibodyFCER2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) antibodyFCER2 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal FCER2-3592 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S52 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S51 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-023M unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 50-331) antibodyFCER2 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA: 1:10000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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: "Comparison of CD23 staining patterns in Merkel cell carcinoma and non-cutaneous small cell carcinoma." in: Journal of cutaneous pathology, Vol. 36, Issue 2, pp. 206-10, (2009) (PubMed).
: "Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China." in: Environmental and molecular mutagenesis, Vol. 50, Issue 4, pp. 285-90, (2009) (PubMed).
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: "Comparison of CD23 staining patterns in Merkel cell carcinoma and non-cutaneous small cell carcinoma." in: Journal of cutaneous pathology, Vol. 36, Issue 2, pp. 206-10, (2009) (PubMed).
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- 抗原
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
- 别名
- FCER2 (FCER2 产品)
- 别名
- BLAST-2 antibody, CD23 antibody, CD23A antibody, CLEC4J antibody, FCE2 antibody, IGEBF antibody, Fcer2a antibody, Fc fragment of IgE receptor II antibody, FCER2 antibody, Fcer2 antibody
- 背景
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Description: The human leukocyte differentiation antigen CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.(supplied by OMIM) . It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a ""membrane bound cytokine," in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro.
Aliases: CD23, FCE2, CD23A, IGEBF, CLEC4J, FCER2
- 分子量
- 37 kDa
- 基因ID
- 2208
- HGNC
- 2208
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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