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- 抗原 See all FABP4 抗体
- FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FABP4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of FABP4 expressed in E. coli.
- 克隆位点
- 9B8D
- 亚型
- IgG1
- Top Product
- Discover our top product FABP4 Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 18, pp. 6970-5, (2006) (PubMed).
: "Adipocyte fatty acid-binding protein: interaction with phospholipid membranes and thermal stability studied by FTIR spectroscopy." in: Biochemistry, Vol. 36, Issue 27, pp. 8311-7, (1997) (PubMed).
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A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 18, pp. 6970-5, (2006) (PubMed).
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- 抗原
- FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))
- 别名
- FABP4 (FABP4 产品)
- 背景
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Description: Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm. It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism. FABP4 encodes the fatty acid binding protein found in adipocytes. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders.
Aliases: aP2, A-FABP, FABP4
- 分子量
- 14 kDa
- 基因ID
- 2167
- HGNC
- 2167
- 途径
- Brown Fat Cell Differentiation
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