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APOB 抗体

APOB 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6G6 unconjugated
产品编号 ABIN968961
发货至: 中国
  • 抗原 See all APOB 抗体
    APOB (Apolipoprotein B (APOB))
    适用
    • 92
    • 25
    • 22
    • 6
    • 3
    宿主
    • 63
    • 34
    • 15
    • 2
    • 1
    小鼠
    克隆类型
    • 78
    • 35
    单克隆
    标记
    • 48
    • 21
    • 17
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APOB antibody is un-conjugated
    应用范围
    • 65
    • 45
    • 33
    • 16
    • 16
    • 15
    • 10
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human ApoB expressed in E. coli.
    克隆位点
    6G6
    亚型
    IgG1
    Top Product
    Discover our top product APOB Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Benn: "Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review." in: Atherosclerosis, Vol. 206, Issue 1, pp. 17-30, (2009) (PubMed).

    Peterson, Mack, Hall, Alsup, Alexander, Sully, Sawires, Cheung, Otto, Gresham: "Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection." in: Cell host & microbe, Vol. 4, Issue 6, pp. 555-66, (2008) (PubMed).

  • 抗原
    APOB (Apolipoprotein B (APOB))
    别名
    ApoB (APOB 产品)
    别名
    FLDB antibody, LDLCQ4 antibody, Ac1-060 antibody, Apo B-100 antibody, ApoB-100 antibody, ApoB-48 antibody, AI315052 antibody, apob-100 antibody, apob-48 antibody, APOB-100 antibody, ApoB(100) antibody, APOB antibody, apolipoprotein B antibody, APOB antibody, Apob antibody
    背景

    Description: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

    Aliases: FLDB, LDLCQ4

    分子量
    516 kDa
    基因ID
    338
    HGNC
    338
    途径
    Lipid Metabolism
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