KIF1A 抗体 (AA 902-1015)
(3 references)-
- 抗原 See all KIF1A 抗体
- KIF1A (Kinesin Family Member 1A (KIF1A))
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抗原表位
- AA 902-1015
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适用
- 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KIF1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 大鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse KIF1A aa. 902-1015
- 克隆位点
- 16-KIF1A
- 亚型
- IgG1
- Top Product
- Discover our top product KIF1A Primary Antibody
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anti-Kinesin Family Member 1A (KIF1A) (AA 35-84) antibody
KIF1A 适用: 小鼠, 人, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, Bat, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 1A (KIF1A) (N-Term) antibodyKIF1A 适用: 小鼠, 人, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968545, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "The UNC-104/KIF1 family of kinesins." in: Current opinion in cell biology, Vol. 13, Issue 1, pp. 36-40, (2001) (PubMed).
: "Defect in synaptic vesicle precursor transport and neuronal cell death in KIF1A motor protein-deficient mice." in: The Journal of cell biology, Vol. 141, Issue 2, pp. 431-41, (1998) (PubMed).
: "The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors." in: Cell, Vol. 81, Issue 5, pp. 769-80, (1995) (PubMed).
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: "The UNC-104/KIF1 family of kinesins." in: Current opinion in cell biology, Vol. 13, Issue 1, pp. 36-40, (2001) (PubMed).
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- 抗原
- KIF1A (Kinesin Family Member 1A (KIF1A))
- 别名
- KIF1A (KIF1A 产品)
- 别名
- ATSV antibody, C630002N23Rik antibody, Gm1626 antibody, Kns1 antibody, C2orf20 antibody, HSN2C antibody, MRD9 antibody, SPG30 antibody, UNC104 antibody, kinesin family member 1A antibody, kinesin family member 1Aa antibody, KIF1A antibody, kif1a antibody, Kif1a antibody, kif1aa antibody
- 背景
- The ability of the kinesin superfamily of motor proteins to hydrolyze ATP as they move progressively along microtubules is important for organelle transport and cell division. Kinesins are grouped according to the location of the motor domain in the N-terminal, middle, or C-terminal region of the protein. A family of N-terminal motor domain kinesin proteins includes KIF1A/1B, KIF3A/3B, KRP85/95, and Klp68d/64. KIF1A and KIF1B are 93% homologous in their N-terminal motor domains, however KIF1A contains a C-terminal PH domain. KIF1A and KIF1B are expressed in neurons where KIF1A is involved in fast anterograde axon transport of synaptic vesicles, and KIF1B is involved in anterograde axon transport of mitochondria. KIF1A associates with organelles that contain synaptotagmin, synaptophysin, and Rab3A. Disruption of the KIF1A gene in mice causes decreases in synaptic vesicle density, neuronal degeneration, and deficits in motor and sensory function. Thus, KIF1A is a critical brain motor protein involved with axonal transport of synaptic vesicle precursors. This antibody is routinely tested by western blot analysis.
- 分子量
- 200 kDa
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