Density Regulated Protein 抗体 (AA 19-201)
(1 reference)-
- 抗原 See all Density Regulated Protein (DENR) 抗体
- Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))
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抗原表位
- AA 19-201
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Density Regulated Protein antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 小鼠, 大鼠, 犬
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human Drp1 aa. 19-201
- 克隆位点
- 22-Drp1
- 亚型
- IgG2a
- Top Product
- Discover our top product DENR Primary Antibody
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anti-Density-Regulated Protein (DENR) (AA 1-198) antibody
DENR 适用: 人, 小鼠, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Density-Regulated Protein (DENR) (AA 1-81) antibodyDENR 适用: 人 ELISA, WB, RNAi 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Density-Regulated Protein (DENR) antibodyDENR 适用: 人 WB, IF, IHC (p), FACS, IF (cc) 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Density-Regulated Protein (DENR) (AA 1-198) antibodyDENR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Density-Regulated Protein (DENR) (AA 1-198) antibodyDENR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Density-Regulated Protein (DENR) (AA 148-198) antibodyDENR 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 山羊, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Density-Regulated Protein (DENR) (AA 47-76) antibodyDENR 适用: 人 WB 宿主: 兔 Polyclonal RB40460 unconjugated
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- 说明
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Related Products: ABIN968551, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "drp, a novel protein expressed at high cell density but not during growth arrest." in: DNA and cell biology, Vol. 17, Issue 5, pp. 437-47, (1998) (PubMed).
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: "drp, a novel protein expressed at high cell density but not during growth arrest." in: DNA and cell biology, Vol. 17, Issue 5, pp. 437-47, (1998) (PubMed).
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- 抗原
- Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))
- 别名
- Density-regulated protein (DENR 产品)
- 别名
- DRP antibody, DRP1 antibody, SMAP-3 antibody, DENR antibody, 1500003K04Rik antibody, drp antibody, drp1 antibody, smap-3 antibody, MGC79758 antibody, MGC107862 antibody, im:6891640 antibody, zgc:113309 antibody, zgc:92629 antibody, denr antibody, Denr antibody, DDBDRAFT_0205981 antibody, DDBDRAFT_0266779 antibody, DDB_0205981 antibody, DDB_0266779 antibody, density regulated re-initiation and release factor antibody, density-regulated protein L homeolog antibody, density-regulated protein antibody, Density-regulated protein antibody, density regulated reinitiation and release factor antibody, DENR antibody, denr.L antibody, Denr antibody, denr antibody, EHI_065830 antibody, CpipJ_CPIJ009942 antibody, MCYG_07531 antibody, Tsp_00169 antibody
- 背景
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In culture, cell density can have profound effects on gene expression, enzymatic activity, and cell signaling pathways. Using differential screening of cDNAs from low-passage nontumorigenic teratocarcinoma cells versus high passage tumorigenic cells, a protein was identified that is regulated in cell-density dependent manner. This protein, density-regulated protein 1 (drp1), contains putative sites for N-myristoylation and phosphorylation sites for cAMP and/or cGMP-dependent kinase, casein kinase II, and PKC. The expression of drp1 is enriched in high density cultures of both nontumorigenic and tumorigenic cell lines and is widely detected in adult organs, especially skeletal and cardiac muscle. In addition, increased expression of drp1 is not due to growth arrest as a result of serum starvation or TGF-beta treatment nor is it a result of factors found in the media of high density cultures. Interestingly, drp1 is expressed highest in skeletal and cardiac muscle where unique cell-cell contacts are involved in muscle cell membrane depolarization and contraction. Thus, drp1 expression may be regulated by signaling pathways related to specific types of cell-cell contacts. This antibody is routinely tested by western blot analysis.
Synonyms: Density Regulated Protein-1 - 分子量
- 27 kDa
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