SLC1A2 抗体 (AA 562-574)
(4 references)-
- 抗原 See all SLC1A2 抗体
- SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))
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抗原表位
- AA 562-574
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SLC1A2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 大鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human EAAT2 aa. 562-574
- 克隆位点
- 20-EAAT2
- 亚型
- IgG1
- Top Product
- Discover our top product SLC1A2 Primary Antibody
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anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (N-Term) antibody
SLC1A2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 460-574) antibodySLC1A2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 160-239) antibodySLC1A2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (2nd Extracellular Loop) antibodySLC1A2 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 306-348) antibodySLC1A2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 144-193) antibodySLC1A2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 467-516) antibodySLC1A2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (C-Term) antibodySLC1A2 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 101-200) antibodySLC1A2 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) antibodySLC1A2 适用: 人 WB 宿主: 小鼠 Monoclonal 4C3 unconjugated
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- 说明
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Related Products: ABIN968545, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "The accessibility of a novel reentrant loop of the glutamate transporter GLT-1 is restricted by its substrate." in: The Journal of biological chemistry, Vol. 275, Issue 13, pp. 9684-9, (2000) (PubMed).
: "Glutamate transporter GLT-1 is transiently localized on growing axons of the mouse spinal cord before establishing astrocytic expression." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 18, Issue 15, pp. 5706-13, (1998) (PubMed).
: "Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1." in: Science (New York, N.Y.), Vol. 276, Issue 5319, pp. 1699-702, (1997) (PubMed).
: "Mouse excitatory amino acid transporter EAAT2: isolation, characterization, and proximity to neuroexcitability loci on mouse chromosome 2." in: Genomics, Vol. 24, Issue 2, pp. 218-24, (1995) (PubMed).
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: "The accessibility of a novel reentrant loop of the glutamate transporter GLT-1 is restricted by its substrate." in: The Journal of biological chemistry, Vol. 275, Issue 13, pp. 9684-9, (2000) (PubMed).
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- 抗原
- SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))
- 别名
- EAAT2 (SLC1A2 产品)
- 别名
- CG3159 antibody, Dmel\\CG3159 antibody, EAAT antibody, dEAAT2 antibody, dEaat2 antibody, Eaat antibody, GB16377 antibody, EAAT2 antibody, SLC1A2 antibody, Eaat2 antibody, Glt antibody, Glt-1 antibody, GLT-1 antibody, 1700091C19Rik antibody, 2900019G14Rik antibody, AI159670 antibody, GLT1 antibody, MGLT1 antibody, eaat2 antibody, fj34b12 antibody, slc1a2 antibody, wu:fj34b12 antibody, zgc:65897 antibody, Excitatory amino acid transporter 2 antibody, excitatory amino acid transporter 2 antibody, solute carrier family 1 member 2 antibody, solute carrier family 1 (glial high affinity glutamate transporter), member 2 antibody, solute carrier family 1 (glial high affinity glutamate transporter), member 2b antibody, Eaat2 antibody, Eaat-2 antibody, SLC1A2 antibody, VDBG_06180 antibody, EUBELI_01747 antibody, Trebr_0139 antibody, Slc1a2 antibody, slc1a2b antibody
- 背景
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Electrogenic-coupled (Na+ and K+) glutamate transporters in nerve terminals and glial cells are essential for maintaining subtoxic levels of extracellular excitatory amino acid neurotransmitters (e.g. glutamate and aspartate). They are also important for modifying synaptic transmission through the cotransport of ions and neurotransmitters. Excitatory amino acid transporter 2 (EAAT2) has 8 alpha-helical transmembrane domains and two reentrant pore-loop-like structures whose conformation is altered during ion neurotransmitter transport. EAAT2 is primarily expressed in astrocytes in adult brain and spinal cord, however it is also found in axons during fetal development. Mice deficient in EAAT2 exhibit lethal epileptic seizures with destruction of hippocampal neurons and an increased susceptibility to cold-induced cortical injury. Such defects in glutamine transporters have also been implicated in stroke, brain trauma, Alzheimer's disease, amyotrophic lateral sclerosis, and Huntington's disease. Thus, glutamine transporters, such as EAAT2, are critical for prevention of neurotoxic brain injury and may regulate glutamatergic synaptic transmission. This antibody is routinely tested by western blot analysis.
Synonyms: Excitatory amino acid transporter 2, Glutamate transporter 1, GLT1 - 分子量
- 66 kDa
- 途径
- Dicarboxylic Acid Transport
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