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CTNND2 抗体 (AA 85-194)

CTNND2 适用: 小鼠, 大鼠 WB, IF 宿主: 小鼠 Monoclonal 30-delta unconjugated
产品编号 ABIN968579
发货至: 中国
  • 抗原 See all CTNND2 抗体
    CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))
    抗原表位
    • 15
    • 14
    • 10
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 85-194
    适用
    • 56
    • 23
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 49
    • 6
    • 1
    小鼠
    克隆类型
    • 51
    • 5
    单克隆
    标记
    • 20
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTNND2 antibody is un-conjugated
    应用范围
    • 27
    • 25
    • 17
    • 13
    • 13
    • 9
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    大鼠
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Mouse delta-Catenin aa. 85-194
    克隆位点
    30-delta
    亚型
    IgG1
    Top Product
    Discover our top product CTNND2 Primary Antibody
  • 说明

    Related Products: ABIN968545, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20°C.
  • Akins, Greer: "Axon behavior in the olfactory nerve reflects the involvement of catenin-cadherin mediated adhesion." in: The Journal of comparative neurology, Vol. 499, Issue 6, pp. 979-89, (2007) (PubMed).

    Izawa, Nishizawa, Ohtakara, Inagaki: "Densin-180 interacts with delta-catenin/neural plakophilin-related armadillo repeat protein at synapses." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 5345-50, (2002) (PubMed).

    Laura, Witt, Held, Gerstner, Deshayes, Koehler, Kosik, Sidhu, Lasky: "The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF." in: The Journal of biological chemistry, Vol. 277, Issue 15, pp. 12906-14, (2002) (PubMed).

    Ho, Zhou, Medina, Goto, Jacobson, Bhide, Kosik: "delta-catenin is a nervous system-specific adherens junction protein which undergoes dynamic relocalization during development." in: The Journal of comparative neurology, Vol. 420, Issue 2, pp. 261-76, (2000) (PubMed).

    Lu, Paredes, Medina, Zhou, Cavallo, Peifer, Orecchio, Kosik: "delta-catenin, an adhesive junction-associated protein which promotes cell scattering." in: The Journal of cell biology, Vol. 144, Issue 3, pp. 519-32, (1999) (PubMed).

  • 抗原
    CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))
    别名
    delta-Catenin (CTNND2 产品)
    别名
    CTNND2 antibody, Catnd2 antibody, Nprap antibody, neurojugin antibody, GT24 antibody, NPRAP antibody, ctnnd2 antibody, si:dkey-40c17.4 antibody, catenin delta 2 antibody, delta-catenin antibody, catenin delta-2 antibody, catenin (cadherin associated protein), delta 2 antibody, catenin (cadherin-associated protein), delta 2b antibody, CTNND2 antibody, BACOIKO001_27 antibody, LOC100070792 antibody, Ctnnd2 antibody, ctnnd2b antibody
    背景
    The catenins (alpha, beta, gamma, delta, p120[ctn]) are cytoplasmic proteins that are related to the Drosophila Armadillo protein. Catenins may have dual roles since they are components of cell-cell adherens junctions and can translocate to the nucleus after stimulation of the Wingless (Wnt-1 homolog) signaling pathway. alpha-Catenin has two subtypes: alphaE-Catenin, which is expressed ubiquitously, and alphaN-Catenin, which is expressed in the nervous system. beta-Catenin binds to the cytoplasmic tail of E-Cadherin at adherens junctions and has been implicated in Wnt-1 signaling. gamma-Catenin is associated with desmoglein in desmosomes and is closely related to beta-Catenin. p120[ctn] is related to both beta- and gamma-catenin and is a substrate of tyrosine kinases localized at adherens junctions. delta-catenin was identified by its ability to bind the Alzheimer's disease-related protein, presenilin-1. It is most closely related to p120[ctn] and the desmosomal protein, p0071. It contains 10 Armadillo (Arm) repeats, as compared to the 13 Arm repeats found in beta-Catenin. delta-Catenin is expressed at high levels in the developing nervous system, where it may be involved in neuronal progenitor cell migration and dendrite development.
    分子量
    160 kDa
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