我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

SLC3A2 抗体 (AA 9-204)

Name: SLC3A2 抗体 (AA 9-204)
SKU: ABIN968570
Availability: OutOfStock

SLC3A2 适用: 化学剂 WB, IF 宿主: 小鼠 Monoclonal 30-CD98HC unconjugated

Western blot analysis of CD98HC on rat liver lysate.

Image no. 3 for anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 9-204) antibody (ABIN968570)

Western Blotting (WB) image for anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 9-204) antibody (ABIN968570)

4 images

(4 references)

产品编号 ABIN968570

发货至: 中国

Datasheet as PDF

抗原 See all SLC3A2 抗体

SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))
抗原表位
15

10

8

6

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 9-204
适用
92

21

20

15
化学剂
宿主
67

39

3
小鼠
Compatible Secondaries
克隆类型
62

43

3
单克隆
标记
54

12

11

6

4

4

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This SLC3A2 antibody is un-conjugated
应用范围
60

39

30

29

26

14

13

13

10

6

6

5

4

3

2

2

2

2
Western Blotting (WB), Immunofluorescence (IF)

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Rat 4F2 hc aa. 9-204

克隆位点

30-CD98HC

亚型

IgG1

Top Product

Discover our top product SLC3A2 Primary Antibody
anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 1-529) antibody
SLC3A2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody
SLC3A2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 360-529) antibody
SLC3A2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 231-280) antibody
SLC3A2 适用: 人, 大鼠, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 213-349) antibody
SLC3A2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody (Biotin)
SLC3A2 适用: 人 FACS, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-108 Biotin

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody (FITC)
SLC3A2 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-108 FITC

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 588-615), (C-Term) antibody
SLC3A2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB22529 unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 285-521) antibody
SLC3A2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody
SLC3A2 适用: 小鼠 FACS, IP, St 宿主: 兔 Chimeric RL388 unconjugated Recombinant Antibody

说明

Related Products: ABIN967389, ABIN968548

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20°C.
Nakamura, Sato, Yang, Miyagawa, Harasaki, Tomita, Matsuoka, Noma, Iwai, Minato: "4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer." in: The Journal of biological chemistry, Vol. 274, Issue 5, pp. 3009-16, (1999) (PubMed).

Tsurudome, Ito, Takebayashi, Okumura, Nishio, Kawano, Kusagawa, Komada, Ito: "Cutting edge: primary structure of the light chain of fusion regulatory protein-1/CD98/4F2 predicts a protein with multiple transmembrane domains that is almost identical to the amino acid transporter E16." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 5, pp. 2462-6, (1999) (PubMed).

Kanai, Segawa, Miyamoto, Uchino, Takeda, Endou: "Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)." in: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 23629-32, (1998) (PubMed).

Fenczik, Sethi, Ramos, Hughes, Ginsberg: "Complementation of dominant suppression implicates CD98 in integrin activation." in: Nature, Vol. 390, Issue 6655, pp. 81-5, (1997) (PubMed).
抗原

SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

别名

CD98HC (SLC3A2 产品)

别名

4F2 antibody, 4F2HC antibody, 4T2HC antibody, CD98 antibody, CD98HC antibody, MDU1 antibody, NACAE antibody, Mdu1 antibody, MGC53951 antibody, slc3a2 antibody, MGC53965 antibody, SLC3A2 antibody, AI314110 antibody, Cd98 antibody, Ly-10 antibody, Ly-m10 antibody, Ly10 antibody, Mgp-2hc antibody, fc65h12 antibody, wu:fc65h12 antibody, id:ibd1327 antibody, sb:cb519 antibody, wu:fe14a07 antibody, wu:fq18d12 antibody, zgc:55813 antibody, solute carrier family 3 member 2 antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog antibody, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2a antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2b antibody, SLC3A2 antibody, Slc3a2 antibody, slc3a2.L antibody, slc3a2.S antibody, slc3a2a antibody, slc3a2b antibody

物质类

Chemical

背景

4F2 antigen (CD98) was identified as a heterodimer consisting of an 80 kDa type II glycosylated integral membrane protein 4F2 heavy chain (4F2 hc) linked by disulfide bonds to a hydrophobic, non-glycosylated, 37 kDa protein 4F2 light chain (4F2 lc). The 4F2 hc colocalizes with cadherins at cell adhesion sites and is required for the intracellular targeting of 4F2 heterodimers. 4F2 hc also associates with beta1 integrins and overexpression of 4F2 reverses the suppression of beta1 integrin activation caused by overexpression of beta1 cytoplasmic domains. 4F2 has also been identified as a fusion regulatory protein FRP-1, since anti-FRP-1 antibodies can induce HIV-mediated cell fusion via an integrin system. 4F2 heterodimers are also important for activation of amino acid transport. 4F2 hc is 30% homologous with the amino acid transport activator D2/rBAT and expression of 4F2 hc in Xenopus oocytes induces system y+L amino acid transport. Thus, 4F2 hc may participate in intracellular trafficking and activation of amino acid transporters, as well as in the regulation of integrin signaling.
Synonyms: 4F2 hc

分子量

80 kDa