Sorting Nexin 1 抗体 (AA 1-108)
(4 references)-
- 抗原 See all Sorting Nexin 1 (SNX1) 抗体
- Sorting Nexin 1 (SNX1)
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抗原表位
- AA 1-108
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Sorting Nexin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human SNX1 aa. 1-108
- 克隆位点
- 51-SNX1
- 亚型
- IgG1
- Top Product
- Discover our top product SNX1 Primary Antibody
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anti-Sorting Nexin 1 (SNX1) (AA 166-275) antibody
SNX1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 6H1 unconjugated
anti-Sorting Nexin 1 (SNX1) (AA 1-522) antibodySNX1 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Sorting Nexin 1 (SNX1) (Internal Region) antibodyVerified SNX1 适用: 人 WB, ELISA, IHC, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Sorting Nexin 1 (SNX1) (AA 1-150) antibodySNX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 1 (SNX1) (AA 1-250) antibodySNX1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 1 (SNX1) (AA 1-522) antibodySNX1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 1 (SNX1) (Internal Region) antibodySNX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 1 (SNX1) (AA 401-522) antibodySNX1 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 1 (SNX1) (AA 124-201) antibodySNX1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 1 (SNX1) antibodySNX1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN967389, ABIN968535
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "The phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradation." in: The Journal of biological chemistry, Vol. 277, Issue 50, pp. 48730-6, (2002) (PubMed).
: "A potential role for protease nexin 1 overexpression in the pathogenesis of scleroderma." in: The Journal of clinical investigation, Vol. 103, Issue 8, pp. 1179-90, (1999) (PubMed).
: "Identification of a family of sorting nexin molecules and characterization of their association with receptors." in: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7278-87, (1998) (PubMed).
: "Enhanced degradation of EGF receptors by a sorting nexin, SNX1." in: Science (New York, N.Y.), Vol. 272, Issue 5264, pp. 1008-10, (1996) (PubMed).
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: "The phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradation." in: The Journal of biological chemistry, Vol. 277, Issue 50, pp. 48730-6, (2002) (PubMed).
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- 抗原
- Sorting Nexin 1 (SNX1)
- 别名
- SNX1 (SNX1 产品)
- 别名
- d254 antibody, sb:cb923 antibody, snx1 antibody, wu:fb40c08 antibody, wu:fj65g09 antibody, MGC82200 antibody, SNX1 antibody, HsT17379 antibody, VPS5 antibody, ARABIDOPSIS THALIANA SORTING NEXIN 1 antibody, ATSNX1 antibody, K16F4.11 antibody, K16F4_11 antibody, sorting nexin 1 antibody, sorting nexin 1a antibody, sorting nexin 1 L homeolog antibody, sorting nexin 1 antibody, sorting nexin-1 antibody, snx1a antibody, snx1.L antibody, SNX1 antibody, snx1 antibody, LOC100380673 antibody, Snx1 antibody
- 背景
- Biological processes such as transmembrane signaling and receptor mediated endocytosis revolve around the function of cell surface receptors. A network of molecular machinery directs the intracellular trafficking of receptors during their biosynthesis and mediates signaling downstream of receptors. The sorting nexins (SNX1, SNX1A, SNX2, SNX3, and SNX4) are a family of intracellular proteins that are thought to direct the sorting of receptor proteins. The SNX proteins contain a conserved 100 amino acid region termed the phox homology (PX) domain and are part of a family of hydrophilic proteins which includes S. cerevisiae proteins that function in protein sorting. SNX1, SNX2, and SNX4 associate predominantly with membranes and bind transmembrane receptors such as those for EGF, PDGF, and insulin. SNX1 directs the EGF receptor to the lysosomes for degradation. SNX2 forms homomeric complexes and heteromeric complexes with SNX1, SNX1A, and SNX4. These complexes are thought to be necessary for efficient protein sorting. Thus, SNX1 and other sorting nexins are thought to play important roles in the specificity of protein trafficking to and from the plasma membrane.
- 分子量
- 74 kDa
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