RAD9A 抗体 (AA 264-370)
(5 references)-
- 抗原 See all RAD9A 抗体
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
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抗原表位
- AA 264-370
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RAD9A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 小鼠, 大鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human hRAD9 aa. 264-370
- 克隆位点
- 56-hRad9
- 亚型
- IgG1
- Top Product
- Discover our top product RAD9A Primary Antibody
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anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 162-391) antibody
RAD9A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (Center) antibodyRAD9A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) antibodyRAD9A 适用: 人, 猴, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5D9 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (pSer387) antibodyRAD9A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (pSer328) antibodyRAD9A 适用: 人 WB, IHC (p), DB 宿主: 兔 Polyclonal RB7115 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 267-341) antibodyRAD9A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (C-Term) antibodyRAD9A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 279-313), (C-Term) antibodyRAD9A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51320 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) antibodyRAD9A 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 29-62), (N-Term) antibodyRAD9A 适用: 小鼠 WB 宿主: 兔 Polyclonal RB52362 unconjugated
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- 说明
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Related Products: ABIN968536, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3292-300, (2002) (PubMed).
: "Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis." in: Nature cell biology, Vol. 2, Issue 1, pp. 1-6, (2000) (PubMed).
: "Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 567-70, (1999) (PubMed).
: "The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1." in: Molecular biology of the cell, Vol. 10, Issue 6, pp. 1985-95, (1999) (PubMed).
: "A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 24, pp. 13890-5, (1997) (PubMed).
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: "c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3292-300, (2002) (PubMed).
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- 抗原
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
- 别名
- hRad9 (RAD9A 产品)
- 别名
- RAD9 antibody, Rad9 antibody, rad9a antibody, MGC89062 antibody, XRad9 antibody, rad9 antibody, RAD9 checkpoint clamp component A antibody, RAD9 checkpoint clamp component B antibody, RAD9 checkpoint clamp component A L homeolog antibody, RAD9A antibody, Rad9a antibody, rad9a antibody, rad9b antibody, rad9a.L antibody
- 背景
- Cell cycle checkpoints are regulatory mechanisms that prevent cell cycle progression in the presence of DNA damage or incompletely replicated DNA. Many of the genes required for cell-cycle arrest are also involved in DNA repair, apoptosis, and induction of transcription. In yeast and humans, hRAD9 plays a role in cell cycle arrest during the G2 phase before entry into mitosis. Phosphorylated hRAD9 is found in the nucleus after DNA damage, and forms DNA damage-responsive complexes with other putative checkpoint control proteins, such as hRAD1 and hHUS1. Expression of hRAD9 in S. pombe rad9::ura4+ cells restores resistance to the DNA synthesis inhibitor hydroxyurea and gamma rays. In addition, hRAD9 binds the anti-apoptotic proteins, Bcl-2 and Bcl-xL , and antisense hRAD9 RNA suppresses DNA-damage induced cell death. Thus, hRAD9 may be an important component of protein complexes that regulate cell cycle progression, as well as apoptosis, in response to DNA damage.
- 分子量
- 60 kDa
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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