TGFB1I1 抗体 (AA 73-186)
(3 references)-
- 抗原 See all TGFB1I1 抗体
- TGFB1I1 (Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1))
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抗原表位
- AA 73-186
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TGFB1I1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 大鼠, 人, 犬
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse Hic-5 aa. 73-186
- 克隆位点
- 34-Hic
- 亚型
- IgG1
- Top Product
- Discover our top product TGFB1I1 Primary Antibody
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anti-Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) (Middle Region) antibody
TGFB1I1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 山羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) (AA 1-444) antibodyTGFB1I1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4B2-D8 unconjugated
anti-Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) (N-Term) antibodyTGFB1I1 适用: 人, 小鼠, 大鼠, 犬, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) (AA 1-444) antibodyTGFB1I1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) (AA 138-200) antibodyTGFB1I1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) (AA 179-228) antibodyTGFB1I1 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 山羊, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) (AA 1-150) antibodyTGFB1I1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) (AA 256-461) antibodyTGFB1I1 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) (AA 291-340) antibodyTGFB1I1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) (Tyr1586) antibodyTGFB1I1 适用: 人, 小鼠, 大鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15426-31, (2002) (PubMed).
: "Identification and characterization of hic-5/ARA55 as an hsp27 binding protein." in: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 39911-8, (2001) (PubMed).
: "Characterization of the TGF beta 1-inducible hic-5 gene that encodes a putative novel zinc finger protein and its possible involvement in cellular senescence." in: The Journal of biological chemistry, Vol. 269, Issue 43, pp. 26767-74, (1994) (PubMed).
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: "Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15426-31, (2002) (PubMed).
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- 抗原
- TGFB1I1 (Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1))
- 别名
- Hic-5 (TGFB1I1 产品)
- 别名
- TGFB1I1 antibody, hic5 antibody, ara55 antibody, hic-5 antibody, tsc-5 antibody, ARA55 antibody, HIC-5 antibody, HIC5 antibody, TSC-5 antibody, Hic5 antibody, Ara55 antibody, Hic-5 antibody, ara-55 antibody, transforming growth factor beta 1 induced transcript 1 antibody, transforming growth factor beta 1 induced transcript 1 L homeolog antibody, TGFB1I1 antibody, tgfb1i1 antibody, Tgfb1i1 antibody, tgfb1i1.L antibody
- 背景
- Focal adhesions are cell structures terminal to the actin-stress fiber bundles. They attach cultured cells to their substratum or extracellular matrix. These adhesions occur through the integrin receptor molecules which link cytoskeletal proteins and extracellular matrix. The intracellular adhesion is composed of a number of proteins such as paxillin, VASP, vinculin, and the focal-adhesion kinases FAK and PYK2/CAKbeta. Hic-5, also described as hydrogen peroxide inducible-mRNA, is a focal adhesion protein that binds to FAK and PYK2. It is ubiquitously expressed with the highest levels found in lung, spleen, and heart. Induction of Hic-5 is accomplished by hydrogen peroxide or TGFbeta1 and is repressed in K-ras transformed cells. Like paxillin, Hic-5 is tyrosine phosphorylated in Src-transformed cells and is highly similar to paxillin in its primary structure. Both proteins contain LIM domains and LD motifs. In addition, Hic-5 localizes to focal adhesions and co-immunoprecipitates with PYK2/CAKbeta in vivo. Thus, Hic-5 may be a substrate for CAKbeta and play a role in signal transduction during proliferation, cell motility, and adhesion.
- 分子量
- 50 kDa
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, VEGF Signaling
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