ITGA2 抗体 (AA 42-245)
(4 references)-
- 抗原 See all ITGA2 抗体
- ITGA2 (Integrin alpha 2 (ITGA2))
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抗原表位
- AA 42-245
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ITGA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human VLA-2alpha aa.42-245
- 克隆位点
- 2-CD49b
- 亚型
- IgG2a
- Top Product
- Discover our top product ITGA2 Primary Antibody
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anti-Integrin alpha 2 (ITGA2) (AA 30-119) antibody
ITGA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 994-1132) antibodyITGA2 适用: 人 FACS, WB, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 8A11A2 unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 170-361) antibodyITGA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) antibodyITGA2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (Internal Region) antibodyITGA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (C-Term) antibodyITGA2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 678-894) antibodyITGA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 74-277) antibodyITGA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 188-365) antibodyITGA2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (C-Term) antibodyITGA2 适用: 人, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968535, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 24, pp. 15578-83, (2002) (PubMed).
: "Radiation-induced activation of nuclear factor-kappaB involves selective degradation of plasma membrane-associated I(kappa)B(alpha)." in: Molecular biology of the cell, Vol. 13, Issue 10, pp. 3431-40, (2002) (PubMed).
: "Crystal structure of the I domain from integrin alpha2beta1." in: The Journal of biological chemistry, Vol. 272, Issue 45, pp. 28512-7, (1997) (PubMed).
: "Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 199, Issue 4, pp. 292-314, (1994) (PubMed).
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: "Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 24, pp. 15578-83, (2002) (PubMed).
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- 抗原
- ITGA2 (Integrin alpha 2 (ITGA2))
- 别名
- CD49b (ITGA2 产品)
- 别名
- BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
- 背景
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Integrins are a family of dimeric proteins that mediate cell-to-cell and extracellular matrix adhesion. They consist of a large alpha chain that is non-covalently associated with a smaller beta chain which is used to define integrin subfamilies. These molecules exhibit a wide range of expression throughout development and adulthood. VLA-2 (very late antigen), a member of the integrin superfamily, was identified on activated T cells, but has since been reported to be on various cell types. VLA-2 is reported to be a heterodimer of integrin alpha2 (CD49b) and integrin beta1 (CD29) subunits. The alpha2 chain contains a large extracellular domain, a transmembrane domain, and a short cytoplasmic tail. VLA-2 functions as a collagen receptor on platelets and fibroblasts, as well as a collagen and laminin receptor on endothelial and epithelial cells. On activated T cells, VLA-2, like LFA-1, exhibits increased number and affinity of ligand binding. Interactions of these molecules with their extracellular matrix ligands is important for directing effector T cells to their target tissues and to provide co-stimulatory signals. Thus, VLA-2 not only plays an important role in cellular adhesion, but may function in intracellular signal transmission. This antibody is routinely tested by western blot analysis.
Synonyms: Integrin alpha2, VLA-2alpha - 分子量
- 150 kDa
- 途径
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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