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BCL2L1 抗体 (AA 18-233)

BCL2L1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 44-Bcl unconjugated
产品编号 ABIN968153
发货至: 中国
  • 抗原 See all BCL2L1 抗体
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    抗原表位
    • 28
    • 19
    • 16
    • 16
    • 13
    • 11
    • 11
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-233
    适用
    • 210
    • 129
    • 113
    • 47
    • 25
    • 11
    • 9
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 157
    • 72
    • 2
    小鼠
    克隆类型
    • 146
    • 85
    单克隆
    标记
    • 122
    • 24
    • 12
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL2L1 antibody is un-conjugated
    应用范围
    • 159
    • 69
    • 62
    • 58
    • 52
    • 33
    • 30
    • 28
    • 28
    • 21
    • 17
    • 10
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应
    小鼠, 大鼠
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human Bcl-xl aa. 18-233
    克隆位点
    44-Bcl
    亚型
    IgG1
    Top Product
    Discover our top product BCL2L1 Primary Antibody
  • 说明

    Related Products: ABIN968536, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Devarajan, De Leon, Talasazan, Schoenfeld, Davidowitz, Burk: "The von Hippel-Lindau gene product inhibits renal cell apoptosis via Bcl-2-dependent pathways." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 40599-605, (2001) (PubMed).

    Oetzel, Jonuleit, Götz, van der Kuip, Michels, Duyster, Hallek, Aulitzky: "The tyrosine kinase inhibitor CGP 57148 (ST1 571) induces apoptosis in BCR-ABL-positive cells by down-regulating BCL-X." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 6, Issue 5, pp. 1958-68, (2000) (PubMed).

    Soini, Kinnula, Kaarteenaho-Wiik, Kurttila, Linnainmaa, Pääkkö: "Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-X, and bax in malignant mesothelioma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 5, Issue 11, pp. 3508-15, (2000) (PubMed).

    Kishimoto, Sprent: "Strong TCR ligation without costimulation causes rapid onset of Fas-dependent apoptosis of naive murine CD4+ T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 4, pp. 1817-26, (1999) (PubMed).

    Anderson, Teutsch, Dong, Wortis: "An essential role for Bruton's [corrected] tyrosine kinase in the regulation of B-cell apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 20, pp. 10966-71, (1996) (PubMed).

  • 抗原
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    别名
    Bcl-x (BCL2L1 产品)
    别名
    BCL-XL/S antibody, BCL2L antibody, BCLX antibody, BCLXL antibody, BCLXS antibody, Bcl-X antibody, PPP1R52 antibody, bcl-xL antibody, bcl-xS antibody, Bcl(X)L antibody, Bcl-XL antibody, Bcl-Xs antibody, Bcl2l antibody, BclX antibody, bcl-x antibody, Bcl-xl antibody, Bclx antibody, bcl-X antibody, Bcl-xL antibody, BCL-XL antibody, BCL2L1 antibody, bcl-XL antibody, bcl-x(l) antibody, bcl-xl/s antibody, bcl-xs antibody, bcl2l antibody, bclx antibody, bclxl antibody, xR11 antibody, bcl-xl antibody, blp1 antibody, cb1021 antibody, zfBLP1 antibody, BCL2 like 1 antibody, BCL2-like 1 antibody, Bcl2-like 1 antibody, BCL2-like 1 L homeolog antibody, bcl2-like 1 antibody, BCL2L1 antibody, Bcl2l1 antibody, bcl2l1 antibody, bcl2l1.L antibody
    背景
    Bcl-x is related to the Bcl-2 protein and can function independently of Bcl-2 in regulating apoptosis (programmed cell death). The bcl-x transcript is expressed in a number of tissues, with the highest levels in the lymphoid and central nervous systems. Two distinct cDNA species, bcl-xL and bcl-xS, have been observed and appear to arise from alternate 5' splice sites located within the first coding exon of the bcl-x gene. Bcl-xL is composed of 233 amino acids and is similar in size and structure to Bcl-2. The Bcl-xS polypeptide shows a deletion of 63 amino acids which consist of the region of Bcl-xL with the highest degree of amino acid identity to Bcl-2. Like Bcl-2, Bcl-xL inhibits cell death upon growth factor withdrawal when transfected into an IL-3-dependent cell line. However, Bcl-xS inhibits Bcl-2 mediated cell survival.
    分子量
    26 kDa
    途径
    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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