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Paxillin 抗体 (AA 1-557)

Name: Paxillin 抗体 (AA 1-557)
SKU: ABIN968066
Availability: OutOfStock

PXN 适用: 人, 小鼠, 大鼠, 小鸡, 犬 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 165-Paxillin unconjugated

Western blot analysis of Paxillin on human endothelial cell lysate.

Immunofluorescent staining of WI38 cells with anti-paxillin.

2 images

(3 references)

产品编号 ABIN968066

发货至: 中国

Datasheet as PDF

抗原 See all Paxillin (PXN) 抗体

Paxillin (PXN)
抗原表位
32

25

17

16

11

9

8

7

7

7

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-557
适用
198

104

72

16

8

7

5

4

3

3

1

1

1

1

1
人, 小鼠, 大鼠, 小鸡, 犬
宿主
190

27

1
小鼠
Compatible Secondaries
克隆类型
176

42
单克隆
标记
121

10

8

8

8

8

8

8

6

6

4

4

4

4

4

2

2

2

1
This Paxillin antibody is un-conjugated
应用范围
166

67

41

40

37

28

27

25

18

14

14

6

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

交叉反应

人, 犬, 大鼠, 小鼠

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Chicken Paxillin aa. 1-557

克隆位点

165-Paxillin

亚型

IgG1

Top Product

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anti-Paxillin (PXN) (AA 201-461) antibody
PXN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 347-578) antibody
PXN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 1-262) antibody
PXN 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 327-568) antibody
PXN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 456-472) antibody
PXN 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody
PXN 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (pTyr118) antibody
PXN 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 1-262) antibody
PXN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (pSer83) antibody
PXN 适用: 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) antibody
PXN 适用: 人 WB, ELISA, IF, IP, ICC 宿主: 小鼠 Monoclonal M107 unconjugated

说明

Related Products: ABIN968536, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
Laukaitis, Webb, Donais, Horwitz: "Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells." in: The Journal of cell biology, Vol. 153, Issue 7, pp. 1427-40, (2001) (PubMed).

Müller, Jung, Wied, Welte, Jordan, Frick: "Redistribution of glycolipid raft domain components induces insulin-mimetic signaling in rat adipocytes." in: Molecular and cellular biology, Vol. 21, Issue 14, pp. 4553-67, (2001) (PubMed).

Salgia, Li, Lo, Brunkhorst, Kansas, Sobhany, Sun, Pisick, Hallek, Ernst: "Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL." in: The Journal of biological chemistry, Vol. 270, Issue 10, pp. 5039-47, (1995) (PubMed).
抗原

Paxillin (PXN)

别名

Paxillin (PXN 产品)

别名

AW108311 antibody, AW123232 antibody, Pax antibody, CG18061 antibody, CG18576 antibody, CG31794 antibody, CT40481 antibody, CT42454 antibody, DPaxillin antibody, DPxn antibody, DPxn37 antibody, Dmel\\CG31794 antibody, Dpax antibody, DpaxA antibody, PDLP antibody, dPax antibody, pax antibody, wu:fw71f12 antibody, PXN antibody, LOC100220858 antibody, paxillin antibody, Paxillin antibody, paxillin S homeolog antibody, paxillin a antibody, PXN antibody, Pxn antibody, Pax antibody, pxn.S antibody, pxna antibody, LOC696336 antibody, pxn antibody

背景

Paxillin, a focal adhesion protein, is a substrate for several tyrosine kinases such as src, FAK, and p120BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. This is consisent with the possibility that paxillin is involved in the regulation of cell morphology. Additionally, because of its SH3 binding domain, paxillin associates tightly with FAK and Crk in an extracellular matrix-independent manner. Paxillin was initially detected in fibroblasts, and its phosphorylation may be important during neurite extension during differentiation. This antibody is routinely tested by western blot analysis.

分子量

68 kDa

途径

MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling