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Ezrin 抗体 (AA 391-515)

Name: Ezrin 抗体 (AA 391-515)
SKU: ABIN968058
Availability: OutOfStock

EZR 适用: 人, 犬 WB, IHC, IP, IF 宿主: 小鼠 Monoclonal 18-Ezrin unconjugated

Western blot analysis of Ezrin on MDCK lysate.

Immunofluorescent staining of HeLa cells with anti-Ezrin antibody.

Image no. 3 for anti-Ezrin (EZR) (AA 391-515) antibody (ABIN968058)

3 images

(5 references)

产品编号 ABIN968058

发货至: 中国

Datasheet as PDF

抗原 See all Ezrin (EZR) 抗体

Ezrin (EZR)
抗原表位
29

16

12

11

9

9

9

8

5

5

4

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 391-515
适用
153

81

74

8

7

7

5

4

3

3

3

1

1

1

1
人, 犬
宿主
141

11

3

2
小鼠
Compatible Secondaries
克隆类型
138

18
单克隆
标记
89

8

7

7

7

7

7

7

4

3

2

2

2

2

2

1
This Ezrin antibody is un-conjugated
应用范围
117

54

25

17

16

13

13

13

10

9

3

2

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

交叉反应

犬

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human Ezrin aa. 391-515

克隆位点

18-Ezrin

亚型

IgG1

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anti-Ezrin (EZR) (AA 1-295) antibody
EZR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 1-586) antibody
EZR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (pTyr478) antibody
EZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

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EZR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CPTC-Ezrin-1 unconjugated

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EZR 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1E11 unconjugated

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EZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

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EZR 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 455-586) antibody
EZR 适用: 人, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 1-251) antibody
EZR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN968619, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
Perez, Kinoshita, Hitoshi, Payan, Kitamura, Nolan, Lorens: "Activation of the PKB/AKT pathway by ICAM-2." in: Immunity, Vol. 16, Issue 1, pp. 51-65, (2002) (PubMed).

Anastasiadis, Moon, Thoreson, Mariner, Crawford, Zheng, Reynolds: "Inhibition of RhoA by p120 catenin." in: Nature cell biology, Vol. 2, Issue 9, pp. 637-44, (2001) (PubMed).

Defacque, Egeberg, Habermann, Diakonova, Roy, Mangeat, Voelter, Marriott, Pfannstiel, Faulstich, Griffiths: "Involvement of ezrin/moesin in de novo actin assembly on phagosomal membranes." in: The EMBO journal, Vol. 19, Issue 2, pp. 199-212, (2000) (PubMed).

Mohler, Kreda, Boucher, Sudol, Stutts, Milgram: "Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50." in: The Journal of cell biology, Vol. 147, Issue 4, pp. 879-90, (1999) (PubMed).

Berryman, Gary, Bretscher: "Ezrin oligomers are major cytoskeletal components of placental microvilli: a proposal for their involvement in cortical morphogenesis." in: The Journal of cell biology, Vol. 131, Issue 5, pp. 1231-42, (1996) (PubMed).
抗原

Ezrin (EZR)

别名

Ezrin (EZR 产品)

别名

CVIL antibody, CVL antibody, VIL2 antibody, ezr antibody, vil2 antibody, wu:fc05c03 antibody, wu:fj31d06 antibody, cvil antibody, cvl antibody, Vil2 antibody, AW146364 antibody, R75297 antibody, p81 antibody, ezr.S antibody, ezrin antibody, ezrin b antibody, ezrin L homeolog antibody, EZR antibody, ezrb antibody, ezr antibody, Ezr antibody, ezr.L antibody

背景

First described as an 80kDa protein concentrated in the apical cytoskeletal region of intestinal brush border cells, ezrin is now recognized as a major substrate of protein tyrosine kinases, such as the epidermal growth factor (EGF) tyrosine kinase. Ezrin is expressed at high levels in intestine, kidney, and placenta. In placenta, ezrin is present as monomers and non-covalent oligomers in tight association with actin microfilaments. In the human epidermoid carcinoma cell line A431, microvilli-like structures appear within 30 seconds after the addition of EGF. These structures give way to membrane ruffles after 2-5 minutes, followed by cell rounding after 10-20 minutes. At the same time, ezrin is recruited into these structures and oligomers are formed following its tyrosine phosphorylation. It is thought that tyrosine phosphorylation triggers the formation of ezrin oligomers.

分子量

80 kDa

途径

Maintenance of Protein Location