SMARCA2 抗体 (AA 1400-1586)
(3 references)-
- 抗原 See all SMARCA2 抗体
- SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))
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抗原表位
- AA 1400-1586
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适用
- 人, 小鼠, 大鼠, 犬, 小鸡
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SMARCA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 交叉反应
- 小鼠, 大鼠, 犬, 小鸡
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human Brm aa. 1400-1586
- 克隆位点
- 24-BRM
- 亚型
- IgG1
- Top Product
- Discover our top product SMARCA2 Primary Antibody
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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 700-1216) antibody
SMARCA2 适用: 人 ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 659-735) antibodySMARCA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D12 unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 58-107) antibodySMARCA2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 小鸡, 猴, 豚鼠, 马, 斑马鱼, Pig, 非洲爪蟾, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 48-214) antibodySMARCA2 适用: 人, 小鼠 WB, IF, ChIP, ICC 宿主: 大鼠 Monoclonal 1H7A10 unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 659-735) antibodySMARCA2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (Internal Region) antibodySMARCA2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (C-Term) antibodySMARCA2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968535, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines." in: Cancer research, Vol. 60, Issue 21, pp. 6171-7, (2000) (PubMed).
: "A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor." in: Nature, Vol. 374, Issue 6522, pp. 562-5, (1995) (PubMed).
: "A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor." in: The EMBO journal, Vol. 12, Issue 11, pp. 4279-90, (1993) (PubMed).
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: "BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines." in: Cancer research, Vol. 60, Issue 21, pp. 6171-7, (2000) (PubMed).
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- 抗原
- SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))
- 别名
- Brm (SMARCA2 产品)
- 别名
- BAF190 antibody, BRM antibody, NCBRS antibody, SNF2 antibody, SNF2L2 antibody, SNF2LA antibody, SWI2 antibody, Sth1p antibody, hBRM antibody, hSNF2a antibody, brm antibody, 2610209L14Rik antibody, SNF2alpha antibody, Snf2l2 antibody, brahma antibody, psa-4 antibody, wu:fa56c07 antibody, wu:fi27f11 antibody, zgc:66238 antibody, Brahma antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 L homeolog antibody, SMARCA2 antibody, smarca2.L antibody, Smarca2 antibody, smarca2 antibody
- 背景
- Several of the SNF and SWI genes of Saccharomyces cerevisiae encode proteins that are involved in the regulation of transcriptional activation. One of these proteins, SNF2/SWI2, has both Drosophila and mammalian homologues, designated brm. The human Brm protein has been reported to be a 180 kDa nuclear factor that acts as a transcriptional activator when fused to a heterologus DNA binding domain. Transfected Brm, expressed in cells lacking endogenous protein, can cooperate with the glucocorticoid receptor (GR) in transcriptional activation. The cooperation between Brm and GR requires the DNA binding domain of GR and the helicase domain and the P/Q-charged domain of Brm. However, Brm does not affect on several other transcription factors. The retinoblastoma protein, Rb, stimulates the transcription of a number of genes. Like Brm, Rb up-regulates glucocorticoid-receptor-mediated transcription. Brm and Rb interact in vitro and in vivo, requiring the Rb-pocket domain and the consensus Rb-binding motif of Brm. This antibody is routinely tested by western blot analysis.
- 分子量
- 180 kDa
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