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SNAP25 抗体 (AA 8-29)

SNAP25 适用: 大鼠, 小鼠 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 20-SP unconjugated
产品编号 ABIN967922
发货至: 中国
  • 抗原 See all SNAP25 抗体
    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
    抗原表位
    • 16
    • 15
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 8-29
    适用
    • 93
    • 63
    • 61
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠, 小鼠
    宿主
    • 95
    • 20
    • 4
    • 4
    • 1
    小鼠
    克隆类型
    • 94
    • 27
    • 1
    单克隆
    标记
    • 70
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SNAP25 antibody is un-conjugated
    应用范围
    • 89
    • 47
    • 27
    • 18
    • 16
    • 14
    • 13
    • 13
    • 13
    • 9
    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应
    大鼠
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Mouse SNAP-25 aa. 8-29
    克隆位点
    20-SP
    亚型
    IgG1
    Top Product
    Discover our top product SNAP25 Primary Antibody
  • 说明

    Related Products: ABIN968545, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Hasegawa, Zinsser, Rhee, Vik-Mo, Davanger, Hay: "Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain." in: Molecular biology of the cell, Vol. 14, Issue 2, pp. 698-720, (2003) (PubMed).

    Torii, Zhao, Yi, Takeuchi, Izumi: "Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a." in: Molecular and cellular biology, Vol. 22, Issue 15, pp. 5518-26, (2002) (PubMed).

    Martinez-Arca, Alberts, Zahraoui, Louvard, Galli: "Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth." in: The Journal of cell biology, Vol. 149, Issue 4, pp. 889-900, (2000) (PubMed).

    Chapman, An, Barton, Jahn: "SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils." in: The Journal of biological chemistry, Vol. 269, Issue 44, pp. 27427-32, (1994) (PubMed).

    Oyler, Higgins, Hart, Battenberg, Billingsley, Bloom, Wilson: "The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations." in: The Journal of cell biology, Vol. 109, Issue 6 Pt 1, pp. 3039-52, (1990) (PubMed).

  • 抗原
    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
    别名
    SNAP-25 (SNAP25 产品)
    别名
    RIC-4 antibody, RIC4 antibody, SEC9 antibody, SNAP antibody, SNAP-25 antibody, bA416N4.2 antibody, dJ1068F16.2 antibody, SNAP-25B antibody, SNAP-25a antibody, ric-4 antibody, ric4 antibody, sec9 antibody, snap-25 antibody, Bdr antibody, sp antibody, fj55h11 antibody, snap25 antibody, wu:fj55h11 antibody, Snap antibody, snap25.2 antibody, wu:fj33h05 antibody, synaptosome associated protein 25 antibody, synaptosome associated protein 25kDa S homeolog antibody, synaptosomal-associated protein, 25kDa antibody, synaptosomal-associated protein 25 antibody, synaptosome associated protein 25kDa antibody, synaptosome associated protein 25kDa L homeolog antibody, zgc:101731 antibody, synaptosomal-associated protein, 25b antibody, SNAP25 antibody, Snap25 antibody, snap25.S antibody, snap25 antibody, BACOIKO003_07 antibody, Tsp_10811 antibody, snap25.L antibody, zgc:101731 antibody, snap25b antibody
    背景
    Release of neurotransmitters from neurons is regulated by exocytosis of synaptic vesicles. This exocytosis is mediated by a complex consisting of membrane components of both the synaptic vesicle and the synaptic plasma membrane. The fusion complex consists of the soluble NSF (N-ethyl-maleimide-sensitive factor) and SNAPs (soluble NSF attachment proteins), along with the receptor proteins (known as SNAREs) synaptobrevin, synaptotagmin, syntaxin, and SNAP-25 (synaptosomal-associated protein of 25 kDa- the name is coincidental to the previously mentioned SNAP” terminology). SNAP-25 and syntaxin are plasmalemmal proteins (designated as t-SNAREs) while synaptobrevin and synaptotagmin are vesicular proteins (designated as v-SNAREs). These four proteins are thought to constitute an initial SNARE docking complex for regulated exocytosis. SNAP-25 lacks a transmembrane domain, but is linked to the membrane by palmitoylated cysteine residues in the central region of the molecule. This antibody is routinely tested by western blot analysis.
    Synonyms: Synaptosomal Associated Protein of 25 kD
    分子量
    25 kDa
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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