ITPR3 抗体 (AA 22-230)
(5 references)-
- 抗原 See all ITPR3 抗体
- ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))
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抗原表位
- AA 22-230
- 适用
- 人, 小鼠, 大鼠, Cow, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ITPR3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 交叉反应
- 牛, 犬, 小鼠, 大鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human IP3R-3 aa. 22-230
- 克隆位点
- 2-IP3R
- 亚型
- IgG2a
- Top Product
- Discover our top product ITPR3 Primary Antibody
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anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) (AA 2411-2758) antibody
ITPR3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) (AA 70-95), (N-Term) antibodyITPR3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) antibodyITPR3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) (AA 1630-1870) antibodyITPR3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) antibodyITPR3 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) (AA 625-675) antibodyITPR3 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968535, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Nuclear and cytosolic calcium are regulated independently." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2975-80, (2003) (PubMed).
: "Intracellular signal transduction during gastrin-induced histamine secretion in rat gastric ECL cells." in: American journal of physiology. Cell physiology, Vol. 282, Issue 2, pp. C374-82, (2002) (PubMed).
: "The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity." in: The Journal of cell biology, Vol. 155, Issue 4, pp. 519-30, (2001) (PubMed).
: "Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium." in: The Journal of biological chemistry, Vol. 269, Issue 2, pp. 1222-30, (1994) (PubMed).
: "Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues." in: The Journal of biological chemistry, Vol. 268, Issue 15, pp. 11356-63, (1993) (PubMed).
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: "Nuclear and cytosolic calcium are regulated independently." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2975-80, (2003) (PubMed).
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- 抗原
- ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))
- 别名
- IP 3R-3 (ITPR3 产品)
- 别名
- Ip3r3 antibody, Itpr-3 antibody, IP3R antibody, IP3R3 antibody, IP3R3X antibody, inositol 1,4,5-triphosphate receptor 3 antibody, inositol 1,4,5-trisphosphate receptor type 3 antibody, inositol 1,4,5-trisphosphate receptor, type 3 antibody, Itpr3 antibody, ITPR3 antibody
- 背景
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Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for many hormones, growth factors, and neurotransmitters. IP3 causes the release of Ca2+ from intracellular stores by binding specific receptors that are coupled to Ca2+ channels. A number of studies have identified a family of at least four IP3 receptors (IP3R). The type III receptor (IP3R-3) has been isolated and characterized in human and rat. IP3 receptors are commonly localized in the endoplasmic reticulum, but have also been identified in the nucleus and the plasma membrane. Co-expression of different IP3 receptors is detected in most tissues and cell lines. Although these receptors appear to have a similar specificity for inositol phosphates, the different receptors have been reported to have different affinities for IP3 as follows: type II > type I > type III. This antibody is routinely tested by western blot analysis.
Synonyms: Inositol 1,4,5-triphosphate receptor type III - 分子量
- 300 kDa
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, BCR Signaling
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