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P-Cadherin 抗体 (AA 72-259)

CDH3 适用: 人, 大鼠 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 56-P unconjugated
产品编号 ABIN967840
发货至: 中国
  • 抗原 See all P-Cadherin (CDH3) 抗体
    P-Cadherin (CDH3)
    抗原表位
    • 16
    • 15
    • 11
    • 9
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 72-259
    适用
    • 101
    • 45
    • 9
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 93
    • 15
    • 2
    小鼠
    克隆类型
    • 94
    • 16
    单克隆
    标记
    • 47
    • 12
    • 11
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P-Cadherin antibody is un-conjugated
    应用范围
    • 98
    • 51
    • 43
    • 41
    • 19
    • 18
    • 13
    • 13
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应
    大鼠
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human P-Cadherin aa. 72-259
    克隆位点
    56-P
    亚型
    IgG1
    Top Product
    Discover our top product CDH3 Primary Antibody
  • 说明

    Related Products: ABIN968533, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20°C.
  • Holsinger, Ward, Duffield, Zachwieja, Jallal: "The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)." in: Oncogene, Vol. 21, Issue 46, pp. 7067-76, (2002) (PubMed).

    Bailey, Biddlestone, Shepherd, Barr, Warner, Jankowski: "Altered cadherin and catenin complexes in the Barrett's esophagus-dysplasia-adenocarcinoma sequence: correlation with disease progression and dedifferentiation." in: The American journal of pathology, Vol. 152, Issue 1, pp. 135-44, (1998) (PubMed).

    Kantak, Kramer: "E-cadherin regulates anchorage-independent growth and survival in oral squamous cell carcinoma cells." in: The Journal of biological chemistry, Vol. 273, Issue 27, pp. 16953-61, (1998) (PubMed).

    Tao, Edwards, Tubb, Wang, Bryan, McCrea: "beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex." in: The Journal of cell biology, Vol. 134, Issue 5, pp. 1271-81, (1996) (PubMed).

    Nose, Nagafuchi, Takeichi: "Isolation of placental cadherin cDNA: identification of a novel gene family of cell-cell adhesion molecules." in: The EMBO journal, Vol. 6, Issue 12, pp. 3655-61, (1988) (PubMed).

  • 抗原
    P-Cadherin (CDH3)
    别名
    P-Cadherin (CDH3 产品)
    别名
    CDH3 antibody, Cadherin-3 antibody, AI385538 antibody, Cadp antibody, Cdhp antibody, P-cadherin antibody, Pcad antibody, CDHP antibody, HJMD antibody, PCAD antibody, E-Cad antibody, E-cadherin antibody, EP-cadherin antibody, XTCAD-1 antibody, c-cadherin antibody, cadherin-1 antibody, cdh1 antibody, cdh1-b antibody, cdh3 antibody, cdhc-A antibody, cdhp antibody, hjmd antibody, l-cam antibody, lcam antibody, pcad antibody, uvo antibody, uvomorulin antibody, xb-cad antibody, xcdh1 antibody, CDH15 antibody, K-CAM antibody, cadherin 3 antibody, cadherin 3 L homeolog antibody, Cadherin-3 antibody, CDH3 antibody, Cdh3 antibody, cdh3.L antibody, cdh-3 antibody
    背景
    Cadherins are a family of transmembrane glycoproteins involved in the Ca2+-dependent cell-cell adhesion that occurs in many tissues. Cadherins are similar in their domain structure, Ca2+ and protease sensitivity, and molecular weight. However, these proteins have distinct tissue expression patterns and immunological reactivities. P-Cadherin is localized in placenta while E-Cadherin and N-Cadherin are found in epithelial and neural tissues, respectively. P-Cadherin is an 829 amino acid polypeptide with a putative signal peptide and precursor region, an extracellular domain containing several internal repeats, and a highly hydrophobic transmembrane region. The cytoplasmic domain provides a link to the cytoskeleton through the associated catenin proteins.
    分子量
    120 kDa
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