RAP1 抗体 (AA 1-184)
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北京 101111
Quick Overview for RAP1 抗体 (AA 1-184) (ABIN967814)
抗原
See all RAP1 (TERF2IP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-184
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交叉反应
- 小鸡, Frog, 小鼠, 大鼠
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human Rap1 aa. 1-184
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亚型
- IgG1
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anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) antibody
TERF2IP 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (Center) antibodyTERF2IP 适用: 人, 小鼠 WB, IP, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 1-280) antibodyTERF2IP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 1-399) antibodyTERF2IP 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1664CT768-14-43 unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 142-191) antibodyTERF2IP 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 猴, 兔, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) antibodyTERF2IP 适用: 人 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (C-Term) antibodyVerified TERF2IP 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 215-264) antibodyTERF2IP 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 212-235) antibodyTERF2IP 适用: 人 WB 宿主: 小鼠 Monoclonal 78B356-1 unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 212-235) antibodyTERF2IP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968537, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "Identification of P2Y12-dependent and -independent mechanisms of glycoprotein VI-mediated Rap1 activation in platelets." in: Blood, Vol. 101, Issue 4, pp. 1409-15, (2003) (PubMed).
: "Nerve growth factor activates persistent Rap1 signaling in endosomes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 15, pp. 5406-16, (2001) (PubMed).
: "c-Src signaling induced by the adapters Sin and Cas is mediated by Rap1 GTPase." in: Molecular and cellular biology, Vol. 20, Issue 19, pp. 7363-77, (2000) (PubMed).
: "Insulin and epidermal growth factor stimulate a conformational change in Rap1 and dissociation of the CrkII-C3G complex." in: The Journal of biological chemistry, Vol. 272, Issue 45, pp. 28179-82, (1997) (PubMed).
: "Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins." in: The Journal of biological chemistry, Vol. 265, Issue 27, pp. 16626-34, (1990) (PubMed).
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- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
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别名
- Rap1
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背景
- Rap1 is a member of the large Ras superfamily of low molecular weight GTP/GDP binding proteins. Like Ras, the Rap proteins cycle between a GDP-bound inactive form and a GTP-bound active form. Since Ras and Rap have the same amino acid sequence in their putative effector domain (aa. 32-40), it seems likely that they perform either similar or antagonistic functions. Rap1A and Rap1B are highly homologous proteins, differing in only 9 of their 184 amino acids. Overexpression of Rap1A (also known as Krev-1) causes reversion of the phenotype of a Ki-Ras-transformed cell line. In vitro, Rap1 can compete efficiently with p21ras for interaction with Ras-GAP. Though they appear to have similar activities, Rap1 and Ras differ in their cellular localization. Ras is found on the inner surface of the plasma membrane while Rap1 is associated with the Golgi. This antibody is routinely tested by western blot analysis.
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分子量
- 21 kDa
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途径
- Cell Division Cycle, Telomere Maintenance
抗原
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