(2 references)-
- 抗原 See all Caspase 4 (CASP4) 抗体
- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Caspase 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 品牌
- BD Pharmingen™
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Recombinant Human Caspase-4
- 克隆位点
- B25-1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CASP4 Primary Antibody
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anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 1-377) antibody
CASP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7G7 unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 290-377) antibodyCASP4 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 82-226) antibodyCASP4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibodyCASP4 适用: 小鼠, 大鼠 WB, ELISA, IP, FACS 宿主: 大鼠 Monoclonal 8A5 unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (Cleaved-Gln81) antibodyCASP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 78-265) antibodyCASP4 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 81-270) antibodyCASP4 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (Internal Region) antibodyVerified CASP4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 111-194) antibodyCASP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (N-Term) antibodyCASP4 适用: 人, 小鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Applications include western blot analysis (1-2 µg/ml). Jurkat T cells (ATCC TIB- 152) and 293 adenovirus-transformed human kidney cells (ATCC CRL-1573) are suggested as positive controls.
- 说明
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Related Products: ABIN967389, ABIN968537
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells." in: The EMBO journal, Vol. 14, Issue 9, pp. 1914-22, (1995) (PubMed).
: "Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases." in: The Journal of biological chemistry, Vol. 270, Issue 26, pp. 15870-6, (1995) (PubMed).
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: "A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells." in: The EMBO journal, Vol. 14, Issue 9, pp. 1914-22, (1995) (PubMed).
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- 抗原
- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
- 别名
- Caspase-4 (CASP4 产品)
- 别名
- ICE(rel)II antibody, ICEREL-II antibody, ICH-2 antibody, Mih1/TX antibody, TX antibody, Casp11 antibody, CASP13 antibody, CASP1 antibody, CASP4 antibody, Caspl antibody, ich-3 antibody, Casp4 antibody, caspase 4 antibody, caspase 4, apoptosis-related cysteine peptidase antibody, caspase-4 antibody, CASP4 antibody, Casp4 antibody, LOC100731032 antibody
- 背景
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Caspase-4 (ICErelII, TX, ICH-2) is a 43 kDa cytosolic protein with homology to the ICE/Ced-3 family of cysteine proteases. Functional similarity with ICE proteases include the ability of Caspase-4 to induce apoptosis when overexpressed. Caspase-4 exhibits protease activity, cleaving both itself and the p30 ICE/caspase-1 proenzyme. However, unlike ICE/caspase-1, caspase-4 displays no IL-1beta processing activity. Caspase-4 mRNA is expressed in most adult human tissues, suggesting a broad tissue distribution. The B25-1 antibody recognizes an ~43 kDa band corresponding to human Caspase-4 (TX). A recombinant human Caspase-4 protein fragment corresponding to amino acids 334-377 was used as immunogen.
Synonyms: TX, Ich-2 - 分子量
- 43 kDa
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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