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LAMP1 抗体

LAMP1 适用: 小鼠 WB, IP, IHC (fro), ICS, IAC 宿主: 大鼠 Monoclonal 1D4B unconjugated
产品编号 ABIN967382
发货至: 中国
  • 抗原 See all LAMP1 抗体
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    适用
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    小鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This LAMP1 antibody is un-conjugated
    应用范围
    • 86
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    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Intracellular Staining (ICS), Immunoaffinity Chromatography (IAC)
    品牌
    BD Pharmingen™
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Plasma membrane fraction of mouse embryo NIH 3T3 cell line
    克隆位点
    1D4B
    亚型
    IgG2a kappa
    Top Product
    Discover our top product LAMP1 Primary Antibody
  • 应用备注
    This antibody conjugate has been tested by intracellular immunofluorescent staining ( Less or equal than 1 µg/million cells, using the Cytofix/Cytoperm™ Kit) with flow cytometric analysis to assure specificity and reactivity.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4° C.
  • Rohrer, Schweizer, Russell, Kornfeld: "The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane." in: The Journal of cell biology, Vol. 132, Issue 4, pp. 565-76, (1996) (PubMed).

    Arterburn, Earles, August: "The disulfide structure of mouse lysosome-associated membrane protein 1." in: The Journal of biological chemistry, Vol. 265, Issue 13, pp. 7419-23, (1990) (PubMed).

    Chen, Chen, DSouza, Murphy, August: "Lysosomal membrane glycoproteins: properties of LAMP-1 and LAMP-2." in: Biochemical Society symposium, Vol. 51, pp. 97-112, (1987) (PubMed).

    Chen, Pan, DSouza, August: "Lysosome-associated membrane proteins: characterization of LAMP-1 of macrophage P388 and mouse embryo 3T3 cultured cells." in: Archives of biochemistry and biophysics, Vol. 239, Issue 2, pp. 574-86, (1985) (PubMed).

  • 抗原
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    别名
    CD107a (LAMP1 产品)
    别名
    CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody
    背景
    The 1D4B antibody recognizes CD107a (Lysosome-Associated Membrane Protein 1, LAMP-1), one of the two major glycoproteins in lysosome membranes which are useful markers to distinguish lysosomes from other organelles. Mouse CD107a consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. Several lines of evidence suggest that cell-surface mouse and human LAMP-1 glycoproteins, the expression of which may correlate with malignant transformation, participate in intercellular adhesion and adhesion to extracellular matrix.
    Synonyms: LAMP-1
    途径
    Autophagy
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