电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ITGB1 抗体

ITGB1 适用: 小鼠 WB, FACS, IP, IHC (p), Func 宿主: 大鼠 Monoclonal 9EG7 unconjugated
产品编号 ABIN967378
发货至: 中国
  • 抗原 See all ITGB1 抗体
    ITGB1 (Integrin beta 1 (ITGB1))
    适用
    • 212
    • 92
    • 71
    • 22
    • 19
    • 18
    • 18
    • 12
    • 10
    • 10
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 159
    • 70
    • 10
    • 5
    • 2
    • 1
    大鼠
    克隆类型
    • 146
    • 96
    • 1
    单克隆
    标记
    • 107
    • 24
    • 23
    • 15
    • 8
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This ITGB1 antibody is un-conjugated
    应用范围
    • 115
    • 114
    • 75
    • 50
    • 30
    • 29
    • 27
    • 27
    • 26
    • 18
    • 15
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)
    品牌
    BD Pharmingen™
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Mouse endothelial cell line
    克隆位点
    9EG7
    亚型
    IgG2a kappa
    Top Product
    Discover our top product ITGB1 Primary Antibody
  • 应用备注
    For IHC, we recommend the use of purified 9EG7 mAb in our special formulation for immunohistochemistry.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4° C.
  • Yashiro, Tai, Toyo-oka, Park, Abe, Hamaoka, Kobayashi, Neben, Fujiwara: "A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co-stimulatory molecules." in: European journal of immunology, Vol. 28, Issue 3, pp. 926-35, (1998) (PubMed).

    Driessens, Van Rijthoven, Kemperman, Roos: "Adhesion of lymphoma cells to fibronectin: differential use of alpha 4 beta 1 and alpha 5 beta 1 integrins and stimulation by the 9EG7 mAb against the murine beta 1 integrin subunit." in: Cell adhesion and communication, Vol. 3, Issue 4, pp. 327-36, (1996) (PubMed).

    Milner, Edwards, Streuli, Ffrench-Constant: "A role in migration for the alpha V beta 1 integrin expressed on oligodendrocyte precursors." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 22, pp. 7240-52, (1996) (PubMed).

    Rich, Van Nood, Lee: "Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8+ T cell growth and apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 7, pp. 2916-23, (1996) (PubMed).

    Kassner, Kawaguchi, Hemler: "Minimum alpha chain cytoplasmic tail sequence needed to support integrin-mediated adhesion." in: The Journal of biological chemistry, Vol. 269, Issue 31, pp. 19859-67, (1994) (PubMed).

    Lenter, Vestweber: "The integrin chains beta 1 and alpha 6 associate with the chaperone calnexin prior to integrin assembly." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 12263-8, (1994) (PubMed).

    Springer: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, (1990) (PubMed).

  • 抗原
    ITGB1 (Integrin beta 1 (ITGB1))
    别名
    CD29 (ITGB1 产品)
    别名
    CD29 antibody, FNRB antibody, GPIIA antibody, MDF2 antibody, MSK12 antibody, VLA-BETA antibody, VLAB antibody, 4633401G24Rik antibody, AA409975 antibody, AA960159 antibody, ENSMUSG00000051907 antibody, Fnrb antibody, Gm9863 antibody, gpIIa antibody, cd29 antibody, fnrb antibody, gpiia antibody, itgb1 antibody, mdf2 antibody, msk12 antibody, vla-beta antibody, vlab antibody, itgb1-a antibody, itgb1-b antibody, integrin subunit beta 1 antibody, integrin beta 1 (fibronectin receptor beta) antibody, integrin subunit beta 1 S homeolog antibody, integrin beta 1 antibody, integrin subunit beta 1 L homeolog antibody, ITGB1 antibody, Itgb1 antibody, itgb1.S antibody, LOC100009173 antibody, itgb1.L antibody
    背景
    The 9EG7 antibody reacts with the 130-kDa integrin beta1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin alpha chains. With alpha1 through alpha6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with alphav (CD51), it forms alphavbeta1 integrin. It also associates with the integrin alpha7 alpha8 and alpha9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, and epithelia. 9EG7 mAb has been shown to inhibit both the alpha6beta1-mediated binding of lymphocytes to endothelial cells and the adhesion mediated by activated, but not unactivated, alpha4beta1-integrin. The source of the immunogen was mouse lymph node-derived endothelial cell line TME.
    Synonyms: Integrin beta1 chain
    途径
    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
You are here:
客服