(3 references)-
- 抗原 See all IL1R1 抗体
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This IL1R1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 品牌
- BD Pharmingen™
- 产品特性
-
1. Please refer to us for technical protocols.
2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- HIL1R-M1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product IL1R1 Primary Antibody
-
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 226-318) antibody
IL1R1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 21-109) antibodyIL1R1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 119-217) antibodyIL1R1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 481-569) antibodyIL1R1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 386-553) antibodyIL1R1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 18-167) antibodyIL1R1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4D2D12 unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (pTyr496) antibodyIL1R1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 226-352) antibodyIL1R1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 474-503) antibodyIL1R1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 18-320) antibodyIL1R1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA Capture: The purified HIL1R-M1 antibody (ABIN967343) is useful as a capture antibody for a sandwich ELISA for measuring human IL-1 receptor I protein levels. Purified HIL1R-M1 antibody can be paired with a biotinylated detecting antibody, with recombinant soluble human IL-1 receptor type I as the standard. Purified HIL1R-M1 antibody should be titrated between 1 - 4 µg/ml to determine its optimal concentration for ELISA capture. To obtain linear standard curves, doubling dilutions of recombinant human IL-1 receptor type I ranging from 3000 to 20 pg/ml are recommended for inclusion in each ELISA plate.
Note: This ELISA antibody pair shows no cross-reactivity with the following recombinant human cytokines: sCD14, CD40, CD40L, IL-1Ra, IL-1RII, IL-1alpha, IL-1beta, IL-2, IL-3, IL-4, sIL-4R, IL-5, IL-6, IL-6R, IL-7, IL-8, IL-10, IL-12p40, IL-12p70, IL-13, IL-15, TNF, LT-alpha, sTNFRI, sTNFRII, IFNgamma, TRAIL, GM-CSF, TGFbeta, Trx Western Blot: The purified HIL1R-M1.1 antibody (ABIN967343) has been reported to be useful for Western blotting, however, the antibody is not routinely tested for this application. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
-
-
: "CD121a." in: Journal of biological regulators and homeostatic agents, Vol. 14, Issue 2, pp. 133-5, (2000) (PubMed).
: "Genomic organization of the type I and type II IL-1 receptors." in: Cytokine, Vol. 7, Issue 6, pp. 483-90, (1996) (PubMed).
: "The two interleukin-1 receptors play different roles in IL-1 actions." in: Clinical immunology and immunopathology, Vol. 72, Issue 1, pp. 9-14, (1994) (PubMed).
-
: "CD121a." in: Journal of biological regulators and homeostatic agents, Vol. 14, Issue 2, pp. 133-5, (2000) (PubMed).
-
- 抗原
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- 别名
- CD121a (IL1R1 产品)
- 别名
- CD121A antibody, D2S1473 antibody, IL-1R-alpha antibody, IL1R antibody, IL1RA antibody, P80 antibody, CD121a antibody, CD121b antibody, IL-iR antibody, Il1r-1 antibody, DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, interleukin 1 receptor type 1 antibody, interleukin 1 receptor, type I antibody, interleukin 1 receptor-like 1 antibody, IL1R1 antibody, Il1r1 antibody, Il1rl1 antibody
- 背景
-
The HIL1R-M1 antibody reacts with recombinant and natural soluble CD121a which is also known as human IL-1 receptor type I proteins. Human IL-1 receptor type I serves as the ligand-binding chain of the IL-1 heterodimer complex. When produced by proteolytic cleavage, soluble forms of the IL-1R type I are found the circulation of healthy individuals and in excessive levels during inflammatory diseases. The human IL-1 receptor type I is also expressed predominantly by T lymphocytes, fibroblasts, and endothelial cells.
Synonyms: IL-1 Receptor Type 1 - 途径
- NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
-
You are here:
