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- 抗原 See all JNK (MAPK8) 抗体
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This JNK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 品牌
- BD Pharmingen™
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human JNK1 fusion protein
- 克隆位点
- G151-333
- 亚型
- IgG1
- Top Product
- Discover our top product MAPK8 Primary Antibody
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anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 245-345) antibody
MAPK8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183), (pTyr185) antibodyMAPK8 适用: 人, 小鼠, 大鼠, 犬, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 1-384) antibodyMAPK8 适用: 人 WB, ELISA, IF, PLA, RNAi 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) antibodyMAPK8 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 201-300) antibodyMAPK8 适用: 人, 小鼠, 大鼠, 小鸡, 犬 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) antibodyMAPK8 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 1-427) antibodyMAPK8 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 318-427) antibodyMAPK8 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 4A11 unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 151-250) antibodyMAPK8 适用: 人, 小鼠, 大鼠, 小鸡, Pig WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183) antibodyMAPK8 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Applications include western blot analysis (0.25-1.0 µg/ml). Other applications not routinely tested include immunoprecipitation (1-2 µg/1x10e6 cells). HeLa control lysate [50 µg (1 µg/µl)] is provided as a western blot positive control (Component No. 51-16516N, store lysate at -20°C). Additional control lysate (ABIN968535) is sold separately.
- 说明
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Related Products: ABIN968535
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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- 抗原
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
- 别名
- JNK1 (MAPK8 产品)
- 别名
- JNK antibody, JNK-46 antibody, JNK1 antibody, JNK1A2 antibody, JNK21B1/2 antibody, PRKM8 antibody, SAPK1 antibody, SAPK1c antibody, AI849689 antibody, Prkm8 antibody, BSK antibody, BSK/DJNK antibody, Bsk antibody, CG5680 antibody, D-JNK antibody, D-junk antibody, DBSK/JNK antibody, DJNK antibody, DJNK/bsk antibody, Dmel\\CG5680 antibody, JNK/SAPK antibody, Jnk antibody, Junk antibody, SAPKa antibody, c-Jun antibody, dJNK antibody, jnk antibody, T10F20.15 antibody, jnk1 antibody, sapk1 antibody, mapk8 antibody, zgc:112379 antibody, JNKb antibody, mapk8b antibody, mitogen-activated protein kinase 8 antibody, Stress-activated protein kinase jnk-1 antibody, basket antibody, Protein kinase superfamily protein antibody, mitogen-activated protein kinase 8 L homeolog antibody, mitogen-activated protein kinase 8b antibody, mitogen-activated protein kinase 8B-like antibody, MAPK8 antibody, jnk-1 antibody, Mapk8 antibody, bsk antibody, ATMPK8 antibody, mapk8.L antibody, mapk8b antibody, LOC109094263 antibody
- 背景
- C-Jun NH2-terminal kinase (JNK1) binds to the c-Jun terminal transactivation domain and phosphorylates it on Ser-63 and Ser-73. Phosphorylation enhances the transcriptional activity of c-Jun. The Ser-Pro-acidic sequence targeted by JNK1 kinase activity establishes it as a proline-directed kinase related to the MAP kinases and cyclin dependent kinases. JNK1 migrates with an apparent molecular weight of 46 kDa by SDS-PAGE. A related protein of 55 kDa has similar kinase activity. JNK1 may act as a tumor promoter in response to UV-irradiation since its activity is potently stimulated by such radiation. This has relevance to the observations that c-Jun transcriptional activity is upregulated by UV irradiation. The G151-333 antibody recognizes both the 46 kDa JNK1 and a related ~55 kDa protein (which may be a modified form of JNK1). It does not cross-react with JNK2. G151-333 precipitates an active kinase. A bacterially expressed fusion protein of human JNK1 was used as immunogen.
- 分子量
- 46 kDa
- 途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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