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TYK2 抗体

This 兔 多克隆 antibody specifically detects TYK2 in IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠. It has been mentioned in 2+ publications
产品编号 ABIN967219
发货至: 中国
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Quick Overview for TYK2 抗体 (ABIN967219)

抗原

See all TYK2 抗体
TYK2 (Tyrosine Kinase 2 (TYK2))

适用

  • 87
  • 36
  • 29
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 75
  • 12

克隆类型

  • 75
  • 13
多克隆

标记

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  • 6
  • 4
  • 4
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TYK2 antibody is un-conjugated

应用范围

  • 68
  • 34
  • 19
  • 16
  • 13
  • 13
  • 9
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  • 5
  • 4
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  • 2
Immunohistochemistry (IHC)
  • 特异性

    TYK2 (Ab-1054) antibody detects endogenous levels of TYK2 protein around tyrosine 1054.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized non-phosphopeptide derived from human TYK2 around the phosphorylation site of tyrosine 1054 (H-E-YP-Y-R).
  • 应用备注

    IHC: 1:50-1:100.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100ug/100ul.

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Zheng, Hu, Quinn, Wang: "Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 6, pp. 721-30, (2005) (PubMed).

    Gauzzi, Velazquez, McKendry, Mogensen, Fellous, Pellegrini: "Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase." in: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20494-500, (1996) (PubMed).

  • 抗原

    TYK2 (Tyrosine Kinase 2 (TYK2))

    别名

    Tyk2

    途径

    JAK/STAT Signaling, Hepatitis C
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