(3 references)-
- 抗原 See all SHPRH 抗体
- SHPRH (SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SHPRH antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human SHPRH (E3 ubiquitin-protein ligase SHPRH )
- Top Product
- Discover our top product SHPRH Primary Antibody
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anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) (AA 1362-1512) antibody
SHPRH 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) antibodySHPRH 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) (AA 1560-1659) antibodySHPRH 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) (AA 251-300) antibodySHPRH 适用: 人, 小鼠, 大鼠, 马, Pig, 兔, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH) (AA 1-100), (AA 1500-1600) antibodySHPRH 适用: 人 WB 宿主: 小鼠 Monoclonal 6D9 unconjugated
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- 限制
- 仅限研究用
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- 储存条件
- 4 °C
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: "Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 34, pp. 12411-6, (2008) (PubMed).
: "Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination." in: The Journal of cell biology, Vol. 175, Issue 5, pp. 703-8, (2006) (PubMed).
: "Cloning and characterization of a novel gene, SHPRH, encoding a conserved putative protein with SNF2/helicase and PHD-finger domains from the 6q24 region." in: Genomics, Vol. 82, Issue 2, pp. 153-61, (2003) (PubMed).
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: "Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 34, pp. 12411-6, (2008) (PubMed).
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- 抗原
- SHPRH (SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH))
- 别名
- SHPRH (SHPRH 产品)
- 别名
- bA545I5.2 antibody, 2610103K11Rik antibody, AA450458 antibody, AU024614 antibody, BC006883 antibody, D230017O13Rik antibody, E130018M05 antibody, SNF2 histone linker PHD RING helicase antibody, SHPRH antibody, Shprh antibody
- 背景
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SHPRH (E3 ubiquitin-protein ligase SHPRH ) involved in DNA repair. Upon genotoxic stress, SHPRH accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of noncanonical poly-ubiquitin chains linked through 'Lys-63'. SHPRH interacts with HLTF, PCNA, UBE2N and RAD18. The RING finger mediates E3 ubiquitin ligase activity. SHPRH belongs to the SNF2/RAD54 helicase family. SHPRH contains 1 helicase ATP-binding domain, 1 helicase C-terminal domain, 1 histone H1 domain, 1 PHD-type zinc finger and 1 RING-type zinc finger.
Synonyms: KIAA2023, SNF2, histone-linker, PHD and RING finger domain-containing helicase.
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