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Retinoblastoma 1 抗体

This 兔 多克隆 antibody specifically detects Retinoblastoma 1 in IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠. It has been mentioned in 3+ publications
产品编号 ABIN966955
发货至: 中国
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Quick Overview for Retinoblastoma 1 抗体 (ABIN966955)

抗原

See all Retinoblastoma 1 (RB1) 抗体
Retinoblastoma 1 (RB1)

适用

  • 288
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  • 119
  • 4
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  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 257
  • 33

克隆类型

  • 212
  • 78
多克隆

标记

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  • 2
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  • 2
  • 2
  • 1
This Retinoblastoma 1 antibody is un-conjugated

应用范围

  • 234
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  • 1
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Immunohistochemistry (IHC)
  • 特异性

    Rb (Ab-807) antibody detects endogenous levels of total Rb protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized non-phosphopeptide derived from human Rb around the phosphorylation site of serine 807 (Y-I-SP-P-L).
  • 应用备注

    WB: 1:500~1:1000
    IHC: 1:50~1:100.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100ug/100ul.

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Roesch, Becker, Meyer, Hafner, Wild, Landthaler, Vogt: "Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 18, Issue 4, pp. 565-72, (2005) (PubMed).

    Knudsen, Wang: "Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation." in: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5771-83, (1997) (PubMed).

    Knudsen, Wang: "Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites." in: The Journal of biological chemistry, Vol. 271, Issue 14, pp. 8313-20, (1996) (PubMed).

  • 抗原

    Retinoblastoma 1 (RB1)

    别名

    Rb

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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