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Retinoblastoma 1 抗体

RB1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 7E4B8 unconjugated
产品编号 ABIN966949
发货至: 中国
  • 抗原 See all Retinoblastoma 1 (RB1) 抗体
    Retinoblastoma 1 (RB1)
    适用
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    宿主
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    • 42
    小鼠
    克隆类型
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    单克隆
    标记
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    This Retinoblastoma 1 antibody is un-conjugated
    应用范围
    • 224
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    Immunohistochemistry (IHC), ELISA
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human RB expressed in E. Coli.
    克隆位点
    7E4B8
    亚型
    IgG1
    Top Product
    Discover our top product RB1 Primary Antibody
  • 应用备注
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    Retinoblastoma 1 (RB1)
    别名
    RB (RB1 产品)
    别名
    OSRC antibody, RB antibody, p105-Rb antibody, pRb antibody, pp110 antibody, Rb antibody, Rb-1 antibody, P105-RB antibody, PP110 antibody, RB11 antibody, zgc:154147 antibody, RB transcriptional corepressor 1 antibody, RB transcriptional corepressor like 1 antibody, retinoblastoma 1 antibody, RB1 antibody, RBL1 antibody, Rb1 antibody, rb1 antibody
    背景
    The Rb protein regulates differentiation, apoptosis, and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1, cyclin D-dependent kinase-mediated phosphorylation of Rb at Ser-795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues. Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tumor suppressor gene(Rb).
    Synonyms: RB, pRb, OSRC, pp110, p105-Rb, RB1
    基因ID
    5925
    途径
    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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