TNFRSF11A 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for TNFRSF11A 抗体 (N-Term) (ABIN966946)
抗原
See all TNFRSF11A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 29-44, N-Term
-
免疫原
- A synthetic peptide corresponding to a sequence at the N-terminal of human RANK (29-44 aa), identical to the related mouse and rat sequence.
-
-
-
-
应用备注
- WB: The detection limit for RANK is approximately 2.5ng/lane under non-reducing and reducing conditions.
-
限制
- 仅限研究用
-
-
-
溶解方式
- 0.2ml of distilled water will yield a concentration of 500µg/ml.
-
缓冲液
- Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
-
储存液
- Thimerosal (Merthiolate), Sodium azide
-
储存条件
- -20 °C
-
-
-
: "RANK-L and RANK: T cells, bone loss, and mammalian evolution." in: Annual review of immunology, Vol. 20, pp. 795-823, (2002) (PubMed).
: "Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families." in: Endocrine reviews, Vol. 20, Issue 3, pp. 345-57, (1999) (PubMed).
-
-
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
-
别名
- RANK
-
背景
- Receptor Activator of Nuclear Factor B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling.RANKL (Receptor Activator for Nuclear Factor B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al. (1997) mapped the RANK gene to 18q22.1.
-
途径
- NF-kappaB Signaling
抗原
-