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XRCC6 抗体 (AA 506-541)

XRCC6 适用: 人, 小鼠, 猴, 非洲爪蟾, Hamster WB, IF, IP, IHC (fp) 宿主: 小鼠 Monoclonal N3H10 unconjugated
产品编号 ABIN966469
发货至: 中国
  • 抗原 See all XRCC6 抗体
    XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
    抗原表位
    • 13
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
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    AA 506-541
    适用
    • 142
    • 39
    • 24
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 猴, 非洲爪蟾, Hamster
    宿主
    • 123
    • 20
    • 2
    小鼠
    克隆类型
    • 115
    • 29
    单克隆
    标记
    • 93
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This XRCC6 antibody is un-conjugated
    应用范围
    • 115
    • 78
    • 72
    • 50
    • 46
    • 24
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    • 14
    • 4
    • 2
    • 2
    • 2
    • 1
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    纯化方法
    Concentrated. Purified from the ascites fluid by Protein A chromatography
    免疫原
    Human placental extract designated as PSE1-PL
    克隆位点
    N3H10
    亚型
    IgG2b
    Top Product
    Discover our top product XRCC6 Primary Antibody
  • 应用备注
    Immunofluorescence
    Immunoprecipitation (Native and denatured)(Use Protein A) (Ab 2µg/mg protein lysate)
    Western blotting: (0.25-0.5 µg/ml for 2hrs at RT)
    Immunohistology (Formalinparaffin)(Ab 1-2g/ml for 30 minute at RT)
    Staining of formalin-fixed tissues is IMPROVED by boiling tissue sections in 10mM citrate buffer, pH 6.0.
    说明

    Cellular Localization: Nuclear.
    Recommended Positive Control: BT474, HEP-G-2 or HeLa Cells, Tonsil

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL.
    缓冲液
    10mM PBS, pH 7.4, with 0.2% BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Wang, Chou, Blankson, Satoh, Knuth, Eisenberg, Pisetsky, Reeves: "Murine monoclonal antibodies specific for conserved and non-conserved antigenic determinants of the human and murine Ku autoantigens." in: Molecular biology reports, Vol. 18, Issue 1, pp. 15-28, (1993) (PubMed).

  • 抗原
    XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
    别名
    Ku (p70) (XRCC6 产品)
    别名
    CTC75 antibody, CTCBF antibody, G22P1 antibody, KU70 antibody, ML8 antibody, TLAA antibody, 70kDa antibody, G22p1 antibody, Ku70 antibody, Kup70 antibody, X-ray repair cross complementing 6 antibody, ATP-dependent DNA helicase II, 70 kDa subunit antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 antibody, XRCC6 antibody, Bm1_41430 antibody, xrcc6.L antibody, Xrcc6 antibody
    背景
    The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
    Also available without BSA and azide at 1mg/ml.
    分子量
    70kDa
    基因ID
    2547
    途径
    DNA Damage Repair
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