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IKBKB 抗体 (C-Term)

IKBKB 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN966372
发货至: 中国
  • 抗原 See all IKBKB 抗体
    IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
    抗原表位
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    C-Term
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This IKBKB antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC)
    免疫原
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to very C-terminal residues of human IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta)
    Top Product
    Discover our top product IKBKB Primary Antibody
  • 限制
    仅限研究用
  • 储存条件
    4 °C
  • Hu, Wang: "IkappaB kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes." in: Gene, Vol. 222, Issue 1, pp. 31-40, (1999) (PubMed).

    Sanz, Sanchez, Lallena, Diaz-Meco, Moscat: "The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation." in: The EMBO journal, Vol. 18, Issue 11, pp. 3044-53, (1999) (PubMed).

    Shindo, Nakano, Sakon, Yagita, Mihara, Okumura: "Assignment of IkappaB kinase beta (IKBKB) to human chromosome band 8p12-->p11 by in situ hybridization." in: Cytogenetics and cell genetics, Vol. 82, Issue 1-2, pp. 32-3, (1998) (PubMed).

    Nemoto, DiDonato, Lin: "Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase." in: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7336-43, (1998) (PubMed).

    Cohen, Henzel, Baeuerle: "IKAP is a scaffold protein of the IkappaB kinase complex." in: Nature, Vol. 395, Issue 6699, pp. 292-6, (1998) (PubMed).

  • 抗原
    IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
    别名
    IKBKB (IKBKB 产品)
    别名
    ikk-beta antibody, ikk2 antibody, ikkb antibody, ikkbeta antibody, IKBKB antibody, IKKB antibody, CG4201 antibody, DIK antibody, DLAK antibody, DmIKK antibody, DmIKKBeta antibody, DmIKKb antibody, DmIKKbeta antibody, DmIkkbeta antibody, Dmel\\CG4201 antibody, Dmikkb antibody, Dmikkbeta antibody, IK antibody, IKK antibody, IKK-beta antibody, IKKb antibody, IKKbeta antibody, IRD-5 antibody, IRD5 antibody, Ik antibody, Ikkb antibody, Ikkbeta antibody, Ird-5 antibody, Ird5 antibody, LRK antibody, Lak antibody, anon-89Bd antibody, dIKK antibody, dIKK-beta antibody, dIKKbeta antibody, dLak antibody, dmIKKbeta antibody, ikk antibody, ird antibody, ird5/DmIkk[beta] antibody, IKK2 antibody, NFKBIKB antibody, AIM-1 antibody, AI132552 antibody, IKK-2 antibody, IKK[b] antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog antibody, inhibitor of nuclear factor kappa B kinase subunit beta antibody, I-kappaB kinase beta antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta antibody, inhibitor of kappaB kinase beta antibody, ikbkb.L antibody, IKBKB antibody, ikbkb antibody, IKKbeta antibody, Ikbkb antibody
    背景
    IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta) acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. IKBKB also phosphorylates NCOA3. Component of the I-kappa-B-kinase (IKK) core complex consists of CHUK, IKBKB and IKBKG, probably four alpha/CHUK-beta/IKBKB dimers are associated with four gamma/IKBKG subunits. The IKK core complex seems to associate with regulatory or adapter proteins to form a IKK-signalosome holo-complex. Part of a complex composed of NCOA2, NCOA3, CHUK/IKKA, IKBKB, IKBKG and CREBBP. Part of a 70-90 kDa complex at least consisting of CHUK/IKKA, IKBKB, NFKBIA, RELA, IKBKAP and MAP3K14.
    Synonyms: IKKB
    途径
    NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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