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Glucagon 抗体

GCG 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2F9 unconjugated
产品编号 ABIN966191
发货至: 中国
  • 抗原 See all Glucagon (GCG) 抗体
    Glucagon (GCG)
    适用
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    宿主
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    小鼠
    克隆类型
    • 82
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    单克隆
    标记
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    This Glucagon antibody is un-conjugated
    应用范围
    • 52
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    ELISA, Western Blotting (WB)
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human GCG expressed in E. Coli.
    克隆位点
    2F9
    亚型
    IgG1
    Top Product
    Discover our top product GCG Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Geliebter, Hashim, Gluck: "Appetite-related gut peptides, ghrelin, PYY, and GLP-1 in obese women with and without binge eating disorder (BED)." in: Physiology & behavior, Vol. 94, Issue 5, pp. 696-9, (2008) (PubMed).

    Arnés, González, Tornero-Esteban, Sancho, Acitores, Valverde, Delgado, Villanueva-Peñacarrillo: "Characteristics of GLP-1 and exendins action upon glucose transport and metabolism in type 2 diabetic rat skeletal muscle." in: International journal of molecular medicine, Vol. 22, Issue 1, pp. 127-32, (2008) (PubMed).

  • 抗原
    Glucagon (GCG)
    别名
    GCG (GCG 产品)
    别名
    GLP1 antibody, GLP2 antibody, GRPP antibody, GLP-1 antibody, Glu antibody, PPG antibody, GCG antibody, gcg-A antibody, gcg1 antibody, glucagon antibody, glucagon L homeolog antibody, GCG antibody, Gcg antibody, gcg.L antibody
    背景
    The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
    Tissue specificity: Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain.
    Synonyms: GLP1, GLP2, GRPP, GCG
    分子量
    21kDa
    基因ID
    2641
    途径
    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
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