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FOXO1 抗体

FOXO1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN966149
发货至: 中国
  • 抗原 See all FOXO1 抗体
    FOXO1 (Forkhead Box O1 (FOXO1))
    适用
    • 231
    • 162
    • 151
    • 48
    • 30
    • 25
    • 18
    • 11
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    • 8
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    人, 小鼠, 大鼠
    宿主
    • 212
    • 21
    • 1
    • 1
    克隆类型
    • 205
    • 30
    多克隆
    标记
    • 105
    • 11
    • 10
    • 9
    • 9
    • 9
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    • 7
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    • 7
    • 5
    • 1
    • 1
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    • 1
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    • 1
    This FOXO1 antibody is un-conjugated
    应用范围
    • 198
    • 91
    • 78
    • 66
    • 57
    • 57
    • 44
    • 33
    • 20
    • 20
    • 8
    • 6
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    Immunohistochemistry (IHC)
    特异性
    FKHR (Ab-319) antibody detects endogenous levels of total FKHR protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR around the phosphorylation site of serine 319.
    Top Product
    Discover our top product FOXO1 Primary Antibody
  • 应用备注
    WB: 1:500~1:1000
    IHC: 1:50~1:100.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100ug/100ul.
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Zhao, Gan, Pan, Kan, Majeski, Adam, Unterman: "Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 839-49, (2004) (PubMed).

    Rena, Woods, Prescott, Peggie, Unterman, Williams, Cohen: "Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion." in: The EMBO journal, Vol. 21, Issue 9, pp. 2263-71, (2002) (PubMed).

    Rena, Prescott, Guo, Cohen, Unterman: "Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting." in: The Biochemical journal, Vol. 354, Issue Pt 3, pp. 605-12, (2001) (PubMed).

    Guo, Rena, Cichy, He, Cohen, Unterman: "Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence." in: The Journal of biological chemistry, Vol. 274, Issue 24, pp. 17184-92, (1999) (PubMed).

  • 抗原
    FOXO1 (Forkhead Box O1 (FOXO1))
    别名
    FKHR (FOXO1 产品)
    别名
    FKH1 antibody, FKHR antibody, FOXO1A antibody, FoxO1a.1 antibody, foxo1 antibody, zgc:153388 antibody, Fkhr antibody, Foxo1a antibody, AI876417 antibody, Afxh antibody, Fkhr1 antibody, fkh1 antibody, fkhr antibody, foxo1a antibody, xFoxO1 antibody, FoxO1A antibody, foxo1a.2 antibody, forkhead box O1 antibody, forkhead box O1 a antibody, forkhead box O1 L homeolog antibody, forkhead box O1 b antibody, FOXO1 antibody, foxo1a antibody, Foxo1 antibody, foxo1 antibody, foxo1.L antibody, foxo1b antibody
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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