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- 抗原 See all p300 (EP300) 抗体
- p300 (EP300) (E1A Binding Protein P300 (EP300))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This p300 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of EP300 expressed in E. Coli.
- 克隆位点
- 7D8A6
- 亚型
- IgG1
- Top Product
- Discover our top product EP300 Primary Antibody
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- 应用备注
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB." in: Molecular and cellular biology, Vol. 28, Issue 4, pp. 1383-92, (2008) (PubMed).
: "p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint." in: The Journal of biological chemistry, Vol. 282, Issue 13, pp. 9678-87, (2007) (PubMed).
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The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB." in: Molecular and cellular biology, Vol. 28, Issue 4, pp. 1383-92, (2008) (PubMed).
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- 抗原
- p300 (EP300) (E1A Binding Protein P300 (EP300))
- 别名
- EP300 (EP300 产品)
- 别名
- KAT3B antibody, RSTS2 antibody, p300 antibody, A430090G16 antibody, A730011L11 antibody, p300 HAT antibody, E1A binding protein p300 antibody, histone acetyltransferase p300 antibody, EP300 antibody, LOC446056 antibody, ep300 antibody, Ep300 antibody
- 背景
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EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional coactivator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
Synonyms: p300, KAT3B - 基因ID
- 2033
- 途径
- p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
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