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p300 抗体

EP300 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7D8A6 unconjugated
产品编号 ABIN966068
发货至: 中国
  • 抗原 See all p300 (EP300) 抗体
    p300 (EP300) (E1A Binding Protein P300 (EP300))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This p300 antibody is un-conjugated
    应用范围
    • 64
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    Western Blotting (WB), ELISA
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of EP300 expressed in E. Coli.
    克隆位点
    7D8A6
    亚型
    IgG1
    Top Product
    Discover our top product EP300 Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Geiger, Sharma, Kim, Nyborg: "The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB." in: Molecular and cellular biology, Vol. 28, Issue 4, pp. 1383-92, (2008) (PubMed).

    Stauffer, Chang, Huang, Dunn, Thayer: "p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint." in: The Journal of biological chemistry, Vol. 282, Issue 13, pp. 9678-87, (2007) (PubMed).

  • 抗原
    p300 (EP300) (E1A Binding Protein P300 (EP300))
    别名
    EP300 (EP300 产品)
    别名
    KAT3B antibody, RSTS2 antibody, p300 antibody, A430090G16 antibody, A730011L11 antibody, p300 HAT antibody, E1A binding protein p300 antibody, histone acetyltransferase p300 antibody, EP300 antibody, LOC446056 antibody, ep300 antibody, Ep300 antibody
    背景
    EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional coactivator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
    Synonyms: p300, KAT3B
    基因ID
    2033
    途径
    p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
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