CREB1 抗体
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北京 101111
Quick Overview for CREB1 抗体 (ABIN965926)
抗原
See all CREB1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- CREB (Ab-129) antibody detects endogenous levels of total CREB protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human CREB around the phosphorylation site of serine 129 (I-L-SP-R-R).
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应用备注
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WB: 1:500~1:1000
IHC: 1:50~1:100. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100ug/100ul.
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 4934-48, (2006) (PubMed).
: "Impaired CREB-1 phosphorylation in antifolate-resistant cell lines with down-regulation of the reduced folate carrier gene." in: Molecular pharmacology, Vol. 66, Issue 6, pp. 1536-43, (2004) (PubMed).
: "PTH induction of transcriptional activity of the cAMP response element-binding protein requires the serine 129 site and glycogen synthase kinase-3 activity, but not casein kinase II sites." in: Endocrinology, Vol. 143, Issue 2, pp. 674-82, (2002) (PubMed).
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- CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
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别名
- CREB
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途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
抗原
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