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CHEK1 抗体

CHEK1 适用: 人, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965885
发货至: 中国
  • 抗原 See all CHEK1 抗体
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    适用
    • 213
    • 119
    • 68
    • 16
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
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    • 1
    • 1
    人, 大鼠
    宿主
    • 222
    • 14
    • 7
    • 5
    克隆类型
    • 210
    • 39
    多克隆
    标记
    • 133
    • 13
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    • 5
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    This CHEK1 antibody is un-conjugated
    应用范围
    • 171
    • 87
    • 53
    • 41
    • 40
    • 36
    • 35
    • 17
    • 16
    • 13
    • 10
    • 7
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    Immunohistochemistry (IHC)
    特异性
    Chk1 (Ab-317) antibody detects endogenous levels of total Chk1 protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    The antiserum was produced against synthesized non-phosphopeptide derived from human Chk1 around the phosphorylation site of serine 317 (S-S-SP-Q-P)
    Top Product
    Discover our top product CHEK1 Primary Antibody
  • 应用备注
    WB: 1:500~1:1000
    IHC: 1:50~1:100.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100ug/100ul.
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Zhang, Otterness, Chiang, Xie, Liu, Mercurio, Abraham: "Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway." in: Molecular cell, Vol. 19, Issue 5, pp. 607-18, (2005) (PubMed).

    Rocha, Garrett, Campbell, Schumm, Perkins: "Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor." in: The EMBO journal, Vol. 24, Issue 6, pp. 1157-69, (2005) (PubMed).

    Clarke, Clarke: "DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system." in: The Biochemical journal, Vol. 388, Issue Pt 2, pp. 705-12, (2005) (PubMed).

    Yu, Chen: "DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains." in: Molecular and cellular biology, Vol. 24, Issue 21, pp. 9478-86, (2004) (PubMed).

  • 抗原
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    别名
    CHK1 (CHEK1 产品)
    别名
    An08g10320 antibody, AO090003000441 antibody, CHK1 antibody, chk1 antibody, C85740 antibody, Chk1 antibody, rad27 antibody, id:ibd2720 antibody, zgc:56093 antibody, CHEK1 antibody, checkpoint kinase 1 antibody, serine/threonine-protein kinase chk1 antibody, serine/threonine-protein kinase Chk1 antibody, CAMK/CAMKL/CHK1 protein kinase Chk1 antibody, checkpoint kinase 1 S homeolog antibody, CHEK1 antibody, ANI_1_2436074 antibody, AOR_1_768154 antibody, PTRG_04183 antibody, SJAG_01680 antibody, PAAG_04978 antibody, MCYG_03290 antibody, VDBG_03742 antibody, chek1.S antibody, Chek1 antibody, chek1 antibody
    途径
    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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