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CHD3 抗体

CHD3 适用: 人, 小鼠 WB, IHC, ELISA, IF, FACS 宿主: 小鼠 Monoclonal 2G4 unconjugated
产品编号 ABIN965879
发货至: 中国
  • 抗原 See all CHD3 抗体
    CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
    适用
    • 29
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    人, 小鼠
    宿主
    • 33
    • 13
    • 1
    小鼠
    克隆类型
    • 33
    • 14
    单克隆
    标记
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    • 2
    • 2
    • 2
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    This CHD3 antibody is un-conjugated
    应用范围
    • 22
    • 13
    • 13
    • 12
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    • 8
    • 7
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    • 4
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CHD3 expressed in E. Coli.
    克隆位点
    2G4
    亚型
    IgG1
    Top Product
    Discover our top product CHD3 Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Burd, Kinyamu, Miller, Archer: "UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, (2008) (PubMed).

    Goehler, Lalowski, Stelzl, Waelter, Stroedicke, Worm, Droege, Lindenberg, Knoblich, Haenig, Herbst, Suopanki, Scherzinger, Abraham, Bauer, Hasenbank, Fritzsche, Ludewig, Büssow, Buessow, Coleman et al.: "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. ..." in: Molecular cell, Vol. 15, Issue 6, pp. 853-65, (2004) (PubMed).

    Lepesheva, Virus, Waterman: "Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function." in: Biochemistry, Vol. 42, Issue 30, pp. 9091-101, (2003) (PubMed).

  • 抗原
    CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
    别名
    CHD3 (CHD3 产品)
    别名
    CG9594 antibody, CHD-3 antibody, CHD3 antibody, DmCHD3 antibody, Dmel\\CG9594 antibody, chd3 antibody, dCHD3 antibody, LOC568230 antibody, zfh antibody, mi-2a antibody, mi2-alpha antibody, Mi-2a antibody, Mi2-ALPHA antibody, ZFH antibody, 2600010P09Rik antibody, AF020312 antibody, Chd7 antibody, Prp7 antibody, Prp9-1 antibody, CG9594 gene product from transcript CG9594-RA antibody, chromodomain helicase DNA binding protein 3 antibody, chromodomain-helicase-DNA-binding protein 3 antibody, Chd3 antibody, CHD3 antibody, chd3 antibody, LOC100480350 antibody
    背景
    This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
    Synonyms: ZFH, Mi-2a, Mi2ALPHA, CHD3
    分子量
    226kDa
    基因ID
    1107
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