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BRCA1 抗体

BRCA1 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965696
发货至: 中国
  • 抗原 See all BRCA1 抗体
    BRCA1 (Breast Cancer 1 (BRCA1))
    适用
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    宿主
    • 162
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    克隆类型
    • 166
    • 35
    多克隆
    标记
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    This BRCA1 antibody is un-conjugated
    应用范围
    • 127
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    Immunohistochemistry (IHC)
    特异性
    BRCA1 (Ab-1423) antibody detects endogenous levels of total BRCA1 protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    The antiserum was produced against synthesized non-phosphopeptide derived from human BRCA1 around the phosphorylation site of serine 1423 (H-G-SP-Q-P).
    Top Product
    Discover our top product BRCA1 Primary Antibody
  • 应用备注
    IHC: 1:50-1:100.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100ug/100ul.
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Greenberg, Sobhian, Pathania, Cantor, Nakatani, Livingston: "Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes." in: Genes & development, Vol. 20, Issue 1, pp. 34-46, (2006) (PubMed).

    Arlt, Xu, Durkin, Casper, Kastan, Glover: "BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function." in: Molecular and cellular biology, Vol. 24, Issue 15, pp. 6701-9, (2004) (PubMed).

    Zhang, Willers, Feng, Ghosh, Kim, Weaver, Chung, Powell, Xia: "Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair." in: Molecular and cellular biology, Vol. 24, Issue 2, pp. 708-18, (2003) (PubMed).

    Kim, Xu, Kastan: "Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage." in: Genes & development, Vol. 16, Issue 5, pp. 560-70, (2002) (PubMed).

    Tibbetts, Cortez, Brumbaugh, Scully, Livingston, Elledge, Abraham: "Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress." in: Genes & development, Vol. 14, Issue 23, pp. 2989-3002, (2000) (PubMed).

  • 抗原
    BRCA1 (Breast Cancer 1 (BRCA1))
    别名
    BRCA1 (BRCA1 产品)
    别名
    BRCAI antibody, BRCC1 antibody, BROVCA1 antibody, IRIS antibody, PNCA4 antibody, PPP1R53 antibody, PSCP antibody, RNF53 antibody, iris antibody, pscp antibody, brcai antibody, brcc1 antibody, rnf53 antibody, brca1 antibody, BRCA1 antibody, LOC100224649 antibody, BRCA1, DNA repair associated antibody, breast cancer 1 antibody, breast cancer 1, early onset antibody, breast cancer 1 L homeolog antibody, BRCA1 antibody, brca1 antibody, LOC755086 antibody, Brca1 antibody, brca1.L antibody
    途径
    Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
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