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BCL 抗体

适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965649
发货至: 中国
  • 抗原
    BCL
    适用
    宿主
    克隆类型
    多克隆
    应用范围
    Immunohistochemistry (IHC)
    特异性
    BCL-2(Ab-70) antibody detects endogenous levels of total BCL-2 protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    This antiserum was produced against synthesized non-phosphopeptide derived from human BCL-2 around the phosphorylation site of serine 70 (R-T-SP-P-L).
  • 应用备注
    IHC: 1:50-1:100.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100ug/100ul.
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Jin, Gao, Flagg, Deng: "Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation." in: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 40209-19, (2004) (PubMed).

    Huang, Cidlowski: "Phosphorylation status modulates Bcl-2 function during glucocorticoid-induced apoptosis in T lymphocytes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 16, Issue 8, pp. 825-32, (2002) (PubMed).

    Yamamoto, Ichijo, Korsmeyer: "BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M." in: Molecular and cellular biology, Vol. 19, Issue 12, pp. 8469-78, (2000) (PubMed).

  • 抗原
    BCL
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