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PNPLA2 抗体 (C-Term)

PNPLA2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965617
发货至: 中国
  • 抗原 See all PNPLA2 抗体
    PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))
    抗原表位
    • 16
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 53
    • 43
    • 11
    • 1
    人, 小鼠, 大鼠
    宿主
    • 53
    • 5
    • 3
    • 2
    • 1
    克隆类型
    • 60
    • 4
    多克隆
    标记
    • 33
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PNPLA2 antibody is un-conjugated
    应用范围
    • 44
    • 30
    • 14
    • 13
    • 13
    • 13
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    纯化方法
    Purified by antigen-specific affinity chromatography.
    免疫原
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ATGL(adipose triglyceride lipase)
    Top Product
    Discover our top product PNPLA2 Primary Antibody
  • 应用备注
    ELISA, Western blotting: 1µg/ml for 2hrs.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    This antibody is stored in PBS, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))
    别名
    ATGL (adipose triglyceride lipase) (PNPLA2 产品)
    别名
    1110001C14Rik antibody, ATGL antibody, PEDF-R antibody, TTS-2.2 antibody, TTS2 antibody, iPLA2zeta antibody, PNPLA2 antibody, pnpla2 antibody, 0610039C21Rik antibody, Atgl antibody, RGD1309044 antibody, patatin like phospholipase domain containing 2 antibody, patatin-like phospholipase domain containing 2 antibody, PNPLA2 antibody, pnpla2 antibody, Pnpla2 antibody
    背景
    ATGL(adipose triglyceride lipase) may function as a lipase and play a role in the adaptive response to a low energy state, such as fasting, by providing fatty acids to other tissues for oxidation. In addition, decreased expression of desnutrin in obesity models suggests its possible contribution to the pathophysiology of obesity. The adipose triglyceride lipase (ATGL) catalyzes the initial step in triglyceride hydrolysis. ATGL contains a patatin domain common to plant acyl-hydrolases. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl-hydrolase activity. Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammals. The iPLA2epsilon (adiponutrin), iPLA2zeta (TTS2.2), and iPLA2eta (GS2) are three novel TAG lipases/acylglycerol transacylases that likely participate in TAG hydrolysis and the acyl-CoA independent transacylation of acylglycerols
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