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ATF2 抗体

There are 5+ publications for this product available. The 兔 多克隆 anti-ATF2 antibody is suitable to detect ATF2 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC.
产品编号 ABIN965612
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ATF2 抗体 (ABIN965612)

抗原

See all ATF2 抗体
ATF2 (Activating Transcription Factor 2 (ATF2))

适用

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人, 小鼠, 大鼠

宿主

  • 366
  • 15
  • 1
  • 1

克隆类型

  • 325
  • 58
多克隆

标记

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This ATF2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 特异性

    ATF-2 (Ab-69 or 51) antibody detects endogenous levels of total ATF-2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized non-phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 69 or 51 (D-Q-TP-P-T).
  • 应用备注

    WB: 1:500~1:1000
    IHC: 1:50~1:100.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100ug/100ul

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Sevilla, Santos, Vega, Lazo: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, (2004) (PubMed).

    Alsayed, Uddin, Mahmud, Lekmine, Kalvakolanu, Minucci, Bokoch, Platanias: "Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid." in: The Journal of biological chemistry, Vol. 276, Issue 6, pp. 4012-9, (2001) (PubMed).

    Gupta, Campbell, Dérijard, Davis: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, (1995) (PubMed).

    van Dam, Wilhelm, Herr, Steffen, Herrlich, Angel: "ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents." in: The EMBO journal, Vol. 14, Issue 8, pp. 1798-811, (1995) (PubMed).

    Abdel-Hafiz, Heasley, Kyriakis, Avruch, Kroll, Johnson, Hoeffler: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, (1993) (PubMed).

  • 抗原

    ATF2 (Activating Transcription Factor 2 (ATF2))

    别名

    ATF2

    途径

    MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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