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ANKH 抗体 (C-Term)

ANKH 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965553
发货至: 中国
  • 抗原 See all ANKH 抗体
    ANKH (Ankylosis, Progressive Homolog (Mouse) (ANKH))
    抗原表位
    • 9
    • 9
    • 6
    • 2
    • 1
    • 1
    C-Term
    适用
    • 22
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 22
    克隆类型
    • 22
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    This ANKH antibody is un-conjugated
    应用范围
    • 20
    • 15
    • 14
    • 14
    • 3
    Immunohistochemistry (IHC)
    纯化方法
    Purified by antigen-specific affinity chromatography.
    免疫原
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ANKH(Progressive ankylosis protein homolog)
    Top Product
    Discover our top product ANKH Primary Antibody
  • 应用备注
    ELISA, Western blotting: 1µg/ml for 2hrs.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    This antibody is stored in PBS, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Williams: "Familial calcium pyrophosphate dihydrate deposition disease and the ANKH gene." in: Current opinion in rheumatology, Vol. 15, Issue 3, pp. 326-31, (2003) (PubMed).

    Nelson, Clegg, Arnold, Ferguson, Bonham, White, Hood, Lin: "The program of androgen-responsive genes in neoplastic prostate epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 18, pp. 11890-5, (2002) (PubMed).

    Williams, Zhang, Timms, Bonavita, Caeiro, Broxholme, Cuthbertson, Jones, Marchegiani, Reginato, Russell, Wordsworth, Carr, Brown: "Autosomal dominant familial calcium pyrophosphate dihydrate deposition disease is caused by mutation in the transmembrane protein ANKH." in: American journal of human genetics, Vol. 71, Issue 4, pp. 985-91, (2002) (PubMed).

  • 抗原
    ANKH (Ankylosis, Progressive Homolog (Mouse) (ANKH))
    别名
    ANKH (ANKH 产品)
    别名
    ANK antibody, CCAL2 antibody, CMDJ antibody, CPPDD antibody, HANK antibody, MANK antibody, Ank antibody, Ankh antibody, D15Ertd221e antibody, ank antibody, mKIAA1581 antibody, ankh antibody, wu:fc08d03 antibody, wu:fj64g09 antibody, zgc:110290 antibody, ANKH inorganic pyrophosphate transport regulator antibody, progressive ankylosis antibody, ANKH inorganic pyrophosphate transport regulator b antibody, ANKH inorganic pyrophosphate transport regulator S homeolog antibody, ANKH inorganic pyrophosphate transport regulator a antibody, ANKH antibody, Ankh antibody, Ank antibody, ankhb antibody, ankh.S antibody, ankha antibody
    背景
    The ANKH (progressive ankylosis protein homolog) is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. The ANKHOR and ANKH-TR are novel genetic markers that are significantly associated with ankylosing spondylitis. Mutation at the mouse `progressive ankylosis' (ank) locus causes a generalized, progressive form of arthritis accompanied by mineral deposition, formation of bony outgrowths, and joint destruction. The human homolog is virtually identical to the mouse protein and ANKH-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.
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