RUNX1T1 抗体
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北京 101111
Quick Overview for RUNX1T1 抗体 (ABIN965546)
抗原
See all RUNX1T1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified by antigen-specific affinity chromatography.
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human AML1-MTG8(acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c)
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anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (Internal Region), (N-Term) antibody
RUNX1T1 适用: 人 ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) antibodyRUNX1T1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5A12 unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (Internal Region) antibodyRUNX1T1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) antibodyRUNX1T1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 1-577) antibodyRUNX1T1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 335-510) antibodyRUNX1T1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IP, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 100-390) antibodyRUNX1T1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (N-Term) antibodyRUNX1T1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 兔, 豚鼠, 马, Cow, Pig, 小鸡, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 288-337) antibodyRUNX1T1 适用: 人, 大鼠, 犬, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 221-270) antibodyRUNX1T1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 兔, 豚鼠, 马, Pig, 小鸡, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- This antibody is stored in PBS, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells." in: BMC cancer, Vol. 4, pp. 44, (2004) (PubMed).
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- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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别名
- AML1-MTG8
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背景
- AML1-MTG8(acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c) is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.
抗原
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