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ABI1 抗体 (C-Term)

ABI1 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965496
发货至: 中国
  • 抗原 See all ABI1 抗体
    ABI1 (Abl-Interactor 1 (ABI1))
    抗原表位
    • 15
    • 12
    • 11
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 62
    • 46
    • 36
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 76
    • 3
    克隆类型
    • 76
    • 3
    多克隆
    标记
    • 44
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABI1 antibody is un-conjugated
    应用范围
    • 61
    • 23
    • 15
    • 15
    • 14
    • 13
    • 13
    • 8
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    纯化方法
    Purified by antigen-specific affinity chromatography.
    免疫原
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ABI1 (Abl-interactor 1)
    Top Product
    Discover our top product ABI1 Primary Antibody
  • 应用备注
    ELISA, Western blotting: 1µg/ml for 2hrs.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    This antibody is stored in PBS, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Yamamoto, Suzuki, Sakaki: "Isolation of hNap1BP which interacts with human Nap1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease." in: Gene, Vol. 271, Issue 2, pp. 159-69, (2001) (PubMed).

    Fan, Goff: "Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases." in: Molecular and cellular biology, Vol. 20, Issue 20, pp. 7591-601, (2000) (PubMed).

    Ziemnicka-Kotula, Xu, Gu, Potempska, Kim, Jenkins, Trenkner, Kotula: "Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton." in: The Journal of biological chemistry, Vol. 273, Issue 22, pp. 13681-92, (1998) (PubMed).

    Taki, Shibuya, Taniwaki, Hanada, Morishita, Bessho, Yanagisawa, Hayashi: "ABI-1, a human homolog to mouse Abl-interactor 1, fuses the MLL gene in acute myeloid leukemia with t(10;11)(p11.2;q23)." in: Blood, Vol. 92, Issue 4, pp. 1125-30, (1998) (PubMed).

    Biesova, Piccoli, Wong: "Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth." in: Oncogene, Vol. 14, Issue 2, pp. 233-41, (1997) (PubMed).

  • 抗原
    ABI1 (Abl-Interactor 1 (ABI1))
    别名
    ABI1 (ABI1 产品)
    别名
    ABI-1 antibody, ABLBP4 antibody, E3B1 antibody, NAP1BP antibody, SSH3BP antibody, SSH3BP1 antibody, NAP1 antibody, Ssh3bp1 antibody, E3b1 antibody, abi1 antibody, wu:fc66g09 antibody, wu:fk56a10 antibody, zgc:73174 antibody, MGC84356 antibody, ABI1 antibody, abi-1 antibody, e3b1 antibody, nap1bp antibody, ssh3bp antibody, ssh3bp1 antibody, wu:fe48a10 antibody, zgc:153534 antibody, DKFZp469P1319 antibody, abl interactor 1 antibody, abl-interactor 1 antibody, abl-interactor 1a antibody, abl interactor 1 S homeolog antibody, abl-interactor 1b antibody, Abl-interactor 1 antibody, Abl interactor 1 antibody, ABI1 antibody, Abi1 antibody, abi1a antibody, abi1.S antibody, abi1 antibody, abi1b antibody, Bm1_44660 antibody, LOAG_04356 antibody
    背景
    The ABI1 (Abl-interactor 1) may act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/ or ABL2. The ABI1 may play a role in regulation of EGF-induced Erk pathway activation. It is involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 It participates in transduction of signals from Ras to Rac.
    途径
    RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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