电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Interleukin 17a 抗体

IL17A 适用: 小鼠 WB 宿主: 大鼠 Monoclonal 20B4-G10-F5 unconjugated
产品编号 ABIN964795
发货至: 中国
  • 抗原 See all Interleukin 17a (IL17A) 抗体
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    适用
    • 90
    • 41
    • 19
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    小鼠
    宿主
    • 62
    • 40
    • 16
    • 7
    • 3
    大鼠
    克隆类型
    • 71
    • 56
    • 1
    单克隆
    标记
    • 62
    • 21
    • 15
    • 10
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Interleukin 17a antibody is un-conjugated
    应用范围
    • 71
    • 60
    • 31
    • 14
    • 11
    • 11
    • 10
    • 10
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  This antibody is specific for mouse Il-17a protein. Cross-reactivity with Il-17a from other sources has not been determined.
    产品特性
    Mouse Interleukin-17A (IL-17A), also known as CTLA-8, is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Mouse IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and mouse IL-17A.
    纯化方法
    purified
    过滤
    Sterile filtered
    免疫原
    This Protein A purified monoclonal antibody was produced in rats by repeated immunizations with full length recombinant mouse IL-17A protein (produced in E.coli) followed by hybridoma development.
    Immunogen Type: RecombinantProtein
    克隆位点
    20B4-G10-F5
    亚型
    IgG2a kappa
    Top Product
    Discover our top product IL17A Primary Antibody
  • 应用备注
    This purified antibody has been tested for use in western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 23 kDa in size corresponding to the mature mouse Il17A protein, a non-glycosylated polypeptide chain consisting of 207 amino acids, by western blotting in appropriate cell lysate or extract.
    说明

    Gene Name: IL17a

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.94 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.
    有效期
    3 months
  • 抗原
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    别名
    IL-17A (IL17A 产品)
    别名
    CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
    背景
    Mouse Interleukin-17A (IL-17A), also known as CTLA-8, is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Mouse IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and mouse IL-17A.
    Synonyms: Interleukin-17A cytokine, IL-17A, IL-17, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8
    基因ID
    16171
    NCBI登录号
    NP_034682
    UniProt
    Q62386
You are here:
客服