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VEGFA 抗体 (Middle Region)

VEGFA 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN955508
发货至: 中国
  • 抗原 See all VEGFA 抗体
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    抗原表位
    • 19
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    AA 147-176, Middle Region
    适用
    • 154
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    宿主
    • 203
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    克隆类型
    • 214
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    • 1
    多克隆
    标记
    • 121
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    This VEGFA antibody is un-conjugated
    应用范围
    • 205
    • 93
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects VEGF-A (Center).
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein A column followed by peptide affinity purification
    免疫原
    KLH conjugated synthetic peptide between 147-176 amino acids from the Central region of human VEGFA
    亚型
    Ig Fraction
    Top Product
    Discover our top product VEGFA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    别名
    VEGF-A (VEGFA 产品)
    背景
    This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.Synonyms: VEGF, VEGFA, VPF, Vascular endothelial growth factor A, Vascular permeability factor
    基因ID
    7422
    NCBI登录号
    NP_001020537
    途径
    RTK signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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