电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

DCC 抗体 (Middle Region)

DCC 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN953653
发货至: 中国
  • 抗原 See all DCC 抗体
    DCC (Deleted in Colorectal Carcinoma (DCC))
    抗原表位
    • 9
    • 8
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 642-670, Middle Region
    适用
    • 47
    • 35
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 56
    • 4
    克隆类型
    • 56
    • 4
    多克隆
    标记
    • 26
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DCC antibody is un-conjugated
    应用范围
    • 44
    • 33
    • 16
    • 5
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Human and Mouse DCC (Center).
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 642-670 amino acids from the Central region of Human DCC. Genename: DCC
    亚型
    Ig Fraction
    Top Product
    Discover our top product DCC Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DCC (Deleted in Colorectal Carcinoma (DCC))
    别名
    Netrin Receptor DCC (DCC 产品)
    别名
    CRC18 antibody, CRCR1 antibody, IGDCC1 antibody, MRMV1 antibody, DCC antibody, zdcc antibody, C030036D22Rik antibody, Igdcc1 antibody, xdcc antibody, XDCCa antibody, dcca-A antibody, Dcc antibody, DCC netrin 1 receptor antibody, deleted in colorectal carcinoma antibody, netrin receptor DCC antibody, DCC antibody, dcc antibody, Dcc antibody, LOC100712666 antibody
    背景
    This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.Synonyms: CRC18, CRCR1, Colorectal cancer suppressor, IGDCC1, Immunoglobulin superfamily DCC subclass member 1, Tumor suppressor protein DCC
    分子量
    158457 Da
    基因ID
    1630
    NCBI登录号
    NP_005206
    途径
    Regulation of Cell Size
You are here:
客服