Macrophage Mannose Receptor 1 抗体 (N-Term)
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- 抗原 See all Macrophage Mannose Receptor 1 (MRC1) 抗体
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
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抗原表位
- AA 358-388, N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Macrophage Mannose Receptor 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody recognizes CD 206 / MRC1 at N-term.
- 交叉反应 (详细)
- Species reactivity (tested):Human, Mouse
- 纯化方法
- Purified through a Protein A column followed by peptide affinity purification
- 免疫原
- Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 358-388aa) of human CD206 / MRC1.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MRC1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) Sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
- 别名
- CD206 / MRC1 (MRC1 产品)
- 别名
- CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mrc1 antibody, MGC86525 antibody, MRC1 antibody, MRC1L-A antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, mannose receptor C-type 1 L homeolog antibody, mediator of replication checkpoint 1 antibody, MRC1 antibody, Mrc1 antibody, mrc1.L antibody, mrc1 antibody
- 背景
- CD206 is a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites. The expression of CD206 is not restricted to macrophages, but is also present on immature dendritic cells (DCs), endothelial cells, kidney mesangial cells, retinal pigment epithelium and tracheal smooth muscle cells.Synonyms: C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, CLEC13D, CLEC13DL, MRC1L1, Macrophage mannose receptor, Macrophage mannose receptor 1-like protein 1
- 基因ID
- 414308
- NCBI登录号
- NP_001009567
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